Abstract:Correspondence, speeches, administrative files, photographs, and audiovisual materials document the professional career of Harold Eliot Varmus, who shared the 1989 Nobel Prize in Physiology and Medicine for the discovery of the cellular origins of cancer, and who later served as Director of the National Institutes of Health from 1993-2000 and President of the Memorial Sloan-Kettering Cancer from 2000-2010. The bulk of the collection consists of Varmus' speeches and professional activities at NIH and MSKCC.