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Adrian Kantrowitz Papers 1944-2004
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Series 6: Heart Transplant (HT), 1961-2004 (Bulk 1966-1969) [series]:

This series provides details on the Kantrowitz research team's experimentation with cardiac transplants in animals and human beings. It consists of surgery records, correspondence, professional and layperson inquiries, memoranda, reports, reprints, abstracts, consent forms, conference material, manuscript drafts, background research, and clippings. The series is divided into the following sub-series: Surgery Data, Administrative Files, Publications, Nancy Ross-Flanigan Files, BBC Documentary, and Michael Meyer Files. The first four sub-series are subdivided further. Materials in the first sub-series are arranged alphabetically by folder title or numerically by experiment numbers. Folders in the second, third, and fourth sub-series are arranged chronologically by date within their respective subdivisions. The final two sub-series are also arranged chronologically by folder date.

Surgery Data contains images of the infant transplantation surgery performed by Kantrowitz on December 6, 1967, as well as the raw data, handwritten notes, and ECG recordings from numerous dog and human infant trials performed by Yasunori Koga and Shigehisa Yagi. The second and third sub-series document internal developments and public discussions regarding animal and human heart transplants, such as the surgeries on the dogs Pirate and Kuru and the ethics of total heart transplants. The Nancy Ross-Flanigan Files contain the planning documents, research, and drafts kept by Ms. Flanigan to help Kantrowitz prepare "America's First Human Heart Transplant -- The Concept, the Planning, and the Furor," a 30th anniversary retrospective on the surgery. The fifth sub-series consists of correspondence regarding a BBC documentary on the history of transplant surgery, and the final sub-series is a group of writings and articles on Kantrowitz's first human heart transplant.

Portions of the series are restricted by HMD's Access to Health Information of Individuals policy (PHI).

 
Surgery Data, 1966-2004 [subseries]:
 
Infant transplantation surgery [subseries]:
12 38
[Infant] heart transplant images 51-360 (1967 Dec 6) [contains DVD], 2004 Jul 30
12 39
Slides 1-120, 1967 Dec 6
12 40
Slides 121-240, 1967 Dec 6
12 41
Slides 241-360, 1967 Dec 6
12 42
Slides, unidentified photographer, 1967-1968, n.d.
12 43
X ray slides by William Neches M.D., pediatric intern (now University of Pittsburgh), 1968
 
Yasunori Koga (Cadaver heart perfusion) [subseries]:
12 44
[ECG recordings during heart perfusion] - Y. Koga, M.D., 1967 Jul-1968 May, n.d.
13 1
Recordings, 1966, n.d.
13 2-3
Recordings of perfusions, 1966
 
Yasunori Koga (Dog) [subseries]:
 
ECG records
13 4
Koga data - Puppy #2021 [contains x-rays], 1966
13 5
Puppy #2022 [contains x-rays], 1966
13 6
Puppy #2025, 1966
13 7
Puppy #2026, 1966
13 8
Puppy #2027 [contains x-rays], 1966
13 9
Puppy #2028 [contains x-rays], 1966
13 10
Puppy #2029 [contains x-rays], 1966
13 11
Puppy #2034, 1966
13 12
Puppy #2035, 1966
13 13
Puppy #2036, 1966
13 14
Dog #8075, 1969 Feb-Mar
 
Perfusion
13 15
Dog perfusion data, perfusion #3001-3007, 1967
13 16
Perfusion recordings 3001-3004, 1967
13 17
Perfusion recordings 3005-3007, 1967
 
ECG recordings after heart transplant
13 18
Dog #6423 [5 rolls], 1968 Mar
13 18
Dog #6492 [5 rolls], 1968 Apr-May
13 18
Dog #6506 [22 rolls], 1968 Apr-May
13 18
Dog #6513 [17 rolls], 1968 Apr-May
13 18
Dog #6592 [8 rolls], 1968 May-Jun
13 18
Dog #6596 [4 rolls], 1968 May
14 1-2
[Various numbers] - Y. Koga, M.D., 1967-1968
 
Yasunori Koga (Human) [subseries]:
14 5
[Heart perfusion], 1967-1968
14 3-4
Heart perfusion (Anencephalic baby) - EKG's [10 rolls], 1968 Jul 25-Dec 24
 
Shigehisa Yagi (Dog) [subseries]:
 
Direct Heart Transplant (DHT) and normothermic perfusion
14 6
[No. 6597] Perfusion (Cadaver heart) 1, 1968 Jun 3
14 7
No. 6613 DHT (puppy), 1968 Jun 24
14 8
No. 6617 DHT (p), 1968 Jun 4
14 9
No. 6624 DHT (p), 1968 May 29
14 10
No. 6643 DHT (p), 1968 Jun 20
14 11
No. 6660 DHT, 1968 Jul 14
14 12
No. 6661 DHT (p), 1968 Jun 11
14 13
No. 6674 DHT (puppy), 1968 Jul 11
14 14
No. 6688 CHT, 1968 Jul 5
14 15
No. 6690 CHT, 1968 Jun 26
14 16
No. 6707 DHT (puppy), 1968 Jul 10
14 17
No. 6743 CHT (puppy), 1968 Jul 26
14 18
No. 6747 DHT (p), 1968 Jul 31
14 19
No. 6748 DHT (puppy), 1968 Aug 5
14 20
No. 6780 DHT (p), 1968 Aug 7
14 21
No. 6805 Perfusion 2, 1968 Aug 21
14 22
No. 6807 DHT (p), 1968 Aug 14
14 23
No. 6820 DHT (p), 1968 Oct 21
14 24
No. 6822 Perfusion 3, 1968 Sep 6
14 25
No. 6824 DHT (p), 1968 Sep 13
14 26
No. 6825 DHT (p), 1968 Aug 23
14 27
No. 6842 DHT (puppy), 1968 Sep 4
14 28
No. 6880 DHT (p), 1968 Sep 25
14 29
No. 6883 DHT (p), 1968 Sep 18
14 30
No. 6898 DHT (p), 1968 Sep 27
14 31
No. 6899 DHT (p), 1968 Sep 30
14 32
No. 6909 DHT (p), 1968 Oct 9
14 33
No. 6921 DHT (p), 1968 Oct 7
14 34
No. 6940 DHT (p), 1968 Oct 30
14 35
No. 6943 Perfusion, 1968 Nov 5
14 36
No. 6954 Perfusion, 1968 Nov 13
14 37
No. 6955 DHT (p), 1968 Nov 1
14 38
No. 6959 Perfusion #20, 1968 Dec 11
14 39
[No. 6972] Cardiopulmonary transplantation, 1968 Nov 6
14 40
No. 6975 Perfusion, 1968 Nov 25
14 41
No. 6976 Perfusion, 1968 Nov 11
14 42
No. 6992 CHT and perfusion, 1968 Nov 27
14 43
No. 6994 CHT and perfusion, 1968 Nov 20
14 44
No. 7031 CHT and perfusion, 1968 Dec 4
14 45
No. 7033 CHT and perfusion #25, 1968 Dec 27
14 46
No. 7044 CHT and perfusion, 1968 Dec 9
14 47
No. 7046 CHT and perfusion, 1968 Dec 30
14 48
No. 7074 Perfusion, 1969 Jan 22
14 49
No. 7075 CHT and perfusion #23, 1968 Dec 18
14 50
No. 8003 Perfusion, 1969 Jan 13
14 51
No. 8005 CHT and perfusion #28, 1969 Jan 10
14 52
No. 8007 CHT and perfusion, 1969 Jan 17
14 53
No. 8008 CHT and perfusion #27, 1969 Jan 8
14 54
No. 8033 CHT and perfusion, 1969 Jan 27
14 55
No. 8037 CHT and perfusion, 1969 Jan 24
14 56
No. 8050 CHT and perfusion, 1969 Jan 29
14 57
No. 8362 DHT (puppy), 1969 Aug 1
14 58
Perfusion #21, 1968 Dec 16
 
Direct Heart Transplant (DHT) and normothermic perfusion tracings
14 59
No. 6624 DHT (Puppy), 5/29/68 operation [10 rolls], 1968 May 31-Jun 13
14 59
No. 6748 DHT (p) EKG, 8/5/68 [9 rolls], 1968 Aug 6-16
14 59
No. 6780 DHT (p) EKG, 8/7/69 [16 rolls], 1968 Aug 8-30
14 59
[No. 6805] Perfusion (Membrane oxygenator) EKG [1 roll], 1968 Aug 21
14 59
No. 6822 Heart perfusion EKG [1 roll], 1968 Sep 6
14 59
No. 6825 DHT (p) EKG, 8/23/68 [2 rolls], 1968 Aug 26-27
14 59
No. 6954 Perfusion EKG [1 roll], 1968 Nov 13
14 59
No. 6959 Perfusion EKG [1 roll], 1968 Dec 11
14 59
No. 6975 Perfusion EKG [1 roll], 1968 Nov 25
14 59
[No. 6976] Heart perfusion EKG [1 roll], 1968 Nov 11
14 59
No. 6994 EKG (During perfusion) CHT (puppy) [1 roll], 1968 Nov 20
14 59
[No. 7031] Cadaver heart perfusion EKG [1 roll], 1968 Dec 4
14 59
No. 7044 CHT perfusion EKG [1 roll], 1968 Dec 9
14 59
No. 7071 EKG [1 roll], 1968 Dec 18
14 59
No. 8362 EKG, 8/1/69 operation [1 roll], 1969 Aug 2
14 59
Perfusion EKG [1 roll], 1968 Dec 16
14 60
Loose EKG rolls, small and medium, 1968 Jun 3-1969 Jan 29
15 1-3
Loose EKG rolls, large, 1968 May 29-1969 Aug 1
16 1
Loose EKG rolls, large, 1968 May 29-1969 Aug 1
 
Hypothermic perfusion transplantation puppy
16 2
# 6097, 1969 Feb 24
16 3
# 7089, 1969 Feb 13
16 4
# 8032, 1969 Feb 7
16 5
# 8036, 1969 Feb 3-4
16 6
# 8072, 8073, 1969 Feb 20
16 7
# 8075, 1969 Feb-Mar
16 8
# 8099, 1969 Feb 26
16 9
# 8115, 1969 Mar 13
16 10
# 8117, 1969 Mar 5
16 11
# 8132, 1969 Mar 10
16 12
# 8133, 1969 Mar 18
16 13
# 8143, 1969 Mar 31
16 14
# 8147, 1969 Mar 20
16 15
# 8159, 1969 Mar 28
16 16
# 8160, 1969 Mar 26
16 17
# 8161, 1969 Apr 11
16 18
# 8174, 1969 Apr 1-2
16 19
# 8185, 1969 Apr 9
16 20
# 8196, 1969 Jun 2
16 21
# 8197, 1969 May 22
16 22
# 8199, 1969 Apr 14
16 23
# 8227, 1969 Jun 24
16 24
# 8229, 1969 May 20
16 25
# 8254, 1969 May 27
16 26
# 8259, 1969 Jun 8-9
16 27
# 8260, 1969 Jun 11-12
16 28
# 8261, 1969 Jul 3
16 29
# 8263, 1969 Jun 20
16 30
# 8323, 1969 Jun 30
16 31
# 8324, 1969 Jun 27
16 32
# 8348, 1969 Jun 15
16 33
# 8356, 1969 Jul 8
16 34
# 8360, 1969 Jul 11
16 35
# 8363, 1969 Jul 23
16 36
# 8366, 1969 Jul 16
16 37
# 8388, 1969 Jul 29
16 38
# 8391, 1969 Jul 25
16 39
# 8394, 1969 Aug 8
16 40
# 8397, 1969 Aug 12
16 41
# 8398, 1969 Aug 14
16 42
# 8400, 8401, 1969 Aug 20-21
16 43
# 8403, 1969 Aug 19
16 44
# 8409, 1969 Aug 28
16 45
# 8411, 1969 Aug 22
16 46
# 8412, 1969 Aug 26
16 47
# 8468, 1969 Sep 11
16 48
# 8470, 1969 Sep 19
16 49
# 8476, 1969 Sep 16
16 50
No number, 1969 Feb 18
16 51
No number, 1969 Mar 7
16 52
No number, 1969 Mar 19
16 53
No number, 1969 Apr 16-17
 
Shigehisa Yagi (Human) [subseries]:
 
Heart perfusion anencephalic baby
16 54
#1, 1968 Jul-Aug
16 55
#2, 1968 Jul-Aug
16 56
#3, 1968 Sep
16 57
#4, 1968 Oct
16 58
#14, 1968 Nov
16 59
#21, 1968 Dec
16 60
#24, 1968 Dec
16 61
No number, 1969 Jan
16 62
No number, 1969 Feb
 
Administrative Files, 1961-1995 [subseries]:
 
Animal [subseries]:
16 63
(Dogs) Long term survivors - Kuru Pirate, 1963-1970
16 64
(Dogs) "Eterna" publicity, 1964
16 65
(Dogs) Nelson correspondence, 1964-1966
16 66
(Animal) Blumenstock inquiry, 1965 Jan
16 67
(Puppy) Co-op Department of Pediatrics, 1965 Jul 8
16 68
[Animal] D'Artagnan: Hematology studies - Hughes Institute, 1965-1966
16 69
Dog Pirate, 1967-1971
16 70
(Dog) "Pirate", 1967-1971
16 71
(Dog) Film - Pirate (Titles), 1968
16 72
[Dog] Kuru, 1970-1972
16 73
Dog - Pirate, 1971
16 74
Dogs Kuru and Pirate, 1971-1972
16 75
(Dog) Sawatani Dx procedures, 1972-1976
16 76
(Dogs) Eterna - Summary of vital information, undated
 
Human-Animal [subseries]:
16 77
National Institutes of Health meeting transplant material - Financial, 1963-1967
16 78
Professional inquiries, 1964-1970
16 79
Imuran, 1965-1968
16 80-81
[Forms, clippings, correspondence, and miscellaneous], 1966-1969, n.d.
16 82
Lay publicity, 1967-1969
16 83
Film requests, 1968
16 84
Photograph requests, 1968 Jan-1969 Mar
 
Human [subseries]:
16 85
Transplantation letters and consent forms, 1966-1967, n.d.
16 86
Inquires to professionals re: donors, 1967 Jan 5
R7 8
Patients, prospective, 1967 Dec-1968 Oct [RESTRICTED PHI POLICY]
16 87
Barnard, C., 1967-1968
16 88
Clinical trial, 1967-1968
16 89
Clinical trial (2nd), 1967-1968
R7 9
Clinical study - Heart perfusion, 1967-1969 [RESTRICTED PHI POLICY]
R7 10
National Institutes of Health clinical research studies - Cost-study patients, 1967-1969 [RESTRICTED PHI POLICY]
R7 11
Transplant clinical trials - Donor registration, 1967-1969 [RESTRICTED PHI POLICY]
 
Lay inquiries
17 1-2
Folder #1 [contains photographs], 1967 Dec-1968 Feb
17 3-4
Folder #2, 1968 Feb
17 5
Folder #3, 1968 Mar-Apr
17 6-7
Folder #4, 1968 May-1969 Mar
17 8
Folder #5, 1969 Apr-1970 May
17 9
National Vital Organ Transplant Foundation, 1968 Jan
17 10
Times letter [re: Harry Schwartz article], 1968 Jan
17 11
Donations, 1968 Jan-Mar
17 12
Block financial analysis, 1968 Jan-May
17 13
Ethics, 1968 Jan-Nov
 
Cape Town Transplant Conference
17 14
Cape Town, South Africa [- Travel, publicity, and correspondence], 1968 Jun-Oct
O1 2-5
Proceedings of Cape Town Transplant Conference (1), 1968 Jul
17 15
[Cape Town Transplant Conference - Correspondence re: transcript], 1968 Aug-Nov
 
Protocol
17 16
Protocol, meeting, 1968 Jan 5
17 17
Protocol (Draft), 1968
17 18
Protocols, 1968-1971
17 19
Protocol original copy, 1971 Apr 30
R7 12
Donor, 1968-1969 [RESTRICTED PHI POLICY]
17 20
Anti Lymphocyte serum, 1968-1972
17 21
Professor DuBost correspondence, 1969 Jan
17 22
Protocols and consent forms, 1971
17 23
Research committee - Protocols and consent forms submitted for approval, 1971
17 24
Ethics, human subjects for research, 1972
17 25
Bank for storage, undated
 
General [subseries]:
 
Articles and clippings
17 26
Press clippings, 1961-1969
17 27
Transplant clippings, 1967-1968
17 28
Originals - Magazine headline articles, 1967-1968, 1983-1988
17 29
Ethics - Saturday Review article, 1968 Jan 6
17 30
Articles, 1968-1970, 1986-1995
17 31
[Clippings], 1985-1987, 1995, n.d.
17 32
Presentations, 1964-1967
O1 6
3 month report - Purchasing dogs, 1966 Oct-Dec
17 33
Vital Organ Transplant Committee of Los Angeles County, 1966-1968
17 34
Downstate Surgical Forum - Orest Zaklynsky, 1967
17 35
Cost analysis, 1967-1969
17 36
National Research Council - Transcript, 1968 May
17 37
New York City Organ Center, 1968-1969
17 38
AK correspondence with Felix Rapaport, 1968-1970
17 39
ACS/NIH Organ Transplant Register, 1972
 
Publications, 1964-1989 [subseries]:
 
By Adrian Kantrowitz [subseries]:
17 40
Biological abstracts, 1964 Dec 14
17 41
Abstract submitted to American College of Surgeons (Not accepted), 1964
17 42
Maimonides Research Society, 1964
17 43
Presented to New York Society for Cardiovascular Surgery - Script for short film, 1964
17 44
Presented to New York Society for Thoracic Surgery, 1964
17 45
Submitted to New York Heart Association (Not accepted), 1964
17 46
["Fate of Orthotopic Canine Heart Transplants",] Journal of Cardiovascular Surgery, 8:155-162, Publication No. 70 [contains photographs], 1964-1967
17 47
["Homotransplantation of the Heart in Puppies Using Profound Hypothermia",] Annals of Surgery, Publication No. 64 [contains photographs], 1965
17 48
"Immediate and Delayed Orthotopic Homotransplantation of the Heart", JAMA Medical News, 1965
17 49
["Immediate and Delayed Orthotopic Homotransplantation of the Heart",] Journal of Thoracic and Cardiovascular Surgery, Publication No. 67, 1965
17 50
Presented to New York Heart Association, 1965
17 51
Submitted to ASAIO (Not accepted), 1965
17 52
Submitted to JAMA (Not accepted) (See Publication No. 70) [contains photographs], 1965-1966
17 53
(Abstract) AATS (American Association for Thoracic Surgery, 1966 Nov-Dec
17 54
Georges Dureau - American Heart Association abstract, 1966
17 55
Year Book publication, 1966
17 56
Histocompatibility - S. Samuels, 1967 May 29
17 57
"Outlook for Cardiac Transplantation" and "Orthotopic Homotransplantation of the Puppy Heart" - Dr. Koga et al, 1967
17 58
Abstracts - ASAIO (American Society for Artificial Internal Organs), 1967
17 59
"La double activate auriculaire apres transplantation cardioaique" - Cabasson et al, Archives des Maladies du Coeur (French), 1968 Dec
17 60
Ethical consideration summary - Dimensions in American Judaism, Volume II Number 4, 1968
17 61
Publication #133 - New York Academy of [Sciences] Sesquicentennial, 1968
17 62
Recent papers, 1987-1989
17 63
"Evaluation of Puppy Cadaver Hearts for Orthotopic Homotransplantation" - Dureau, Schilt, Khalil, Okura, Kantrowitz, undated
 
By others [subseries]:
17 64
"Electrocardiographic Studies of Cardiac Orthotopic Homotransplantation 1. The Normal Puppy" - Cabasson and Joos, 1967
17 65
"The Heart of the Anencephalic Infant: A Possible Donor for Cardiac Transplantation", [1969?]
17 66
Abstracts on heart transplant, 1969-1971
17 67
"Supplying Organs for Transplantation" - Michigan Law Review, 1970 Apr
17 68
Journal of Heart Transplantation, Volume IV Number 2, International Society of Heart Transplantation, 1985 Feb
 
Nancy Ross-Flanigan Files, 1963-1998 [subseries]:
17 69
"America's First Human Heart Transplant - The Concept, the Planning, and the Furor" [contains diskette], 1998
 
Background research [subseries]:
17 70
NRF copies of background for first infant transplant - Reprints - References, 1963-1976, 1988, n.d.
17 71
AK presentations relating to heart transplantation, 1964-1968
18 1
Background information for first heart transplant (infant), 1966-1968, 1995-1997
18 2
NRF copies of articles, [ca.1966]-1971, 1985
18 3
Norman Shumway news release comments, 1967 Nov 20
18 4
Bethesda cardiac transplant conference [contains photograph], 1968 Sep
18 5
Reprints of heart transplantation articles, 1968
18 6
Miscellaneous heart transplant items, 1968, 1984-1986
18 7
Heart transplantation articles, 1985-1995
18 8
Abstract by Dr. Hans Carstensen, 1995
18 9
Adrian Kantrowitz curriculum vitae, 1997 Jun
 
Drafts [subseries]:
18 10-11
Heart Transplant Retrospective Volume I, 1996 Dec 6-1997 Feb 6
18 12-13
Heart Transplant Retrospective Volume II, 1997 Jun 20-Jul 24
18 14
Michael Meyer's review comments on draft 6 Ross-Flanigan paper, 1997 Jun-Jul
18 15
Talks relating to heart transplantation - 1965-1967 listing, 1997 Jul 24
18 16
Ross-Flanigan transplant paper draft 7, 1997 Jul 31
18 17-18
[Ross-Flanigan transplant paper drafts 8-9, William Neches copy], 1997 Aug 14-1998 Jan 15
18 19
Jordan Haller review of Ross-Flanigan paper, 1997 Aug
18 20
Ross-Flanigan transplant paper drafts 10-12, 1997 Oct 8-Nov 5
 
General [subseries]:
18 21
Detailed tabulation of replies to questions #5-16 - Main report Q #1-4, 1969-1971
18 22
[Heart failure] abstract and references [contains diskette], 1985, 1996-1997
18 23
Disks, [notes, misc. used in] transplant paper, 1986, 1997, n.d.
R7 13
[Parents' addresses, letters], 1995-1997 [RESTRICTED PHI POLICY]
18 24
NRF - Transplants - Miscellaneous, 1996 Dec 11
18 25
Heart transplant - Helen Taussig correspondence, 1997 Feb-Mar
18 26
Ross-Flanigan letter to Mr. Bashaw requesting permission to use "Statement of Responsibility", 1997 Jul 31
18 27
Correspondence to locate info needed for transplant paper, 1997
18 28
Nancy Ross-Flanigan To Do Lists, 1997
18 29
Ross-Flanigan paper background notes - Contact numbers, 1997
 
References [subseries]:
18 30-32
Heart transplantation references by years (1905-1970), 1996 Nov 22
18 33
Ross-Flanigan references of Barnard papers, 1997 Feb 6
18 34
Heart transplant final papers - Ross-Flanigan [- List and source information], 1997
18 35
Source materials cited in transplant article, 1997
18 36
References cited list, undated
 
BBC Documentary, 1995-1997 [subseries]:
18 37
BBC (Richard Pendry) - History of heart transplant surgery, 1995 Feb-May
O1 7
Richard Pendry travel schedule, 1995 Mar-Apr
18 38
BBC and PBS documentary films on the history of transplant surgery, 1995 Mar-May
R7 14
Correspondence - BBC producers and [donor parents], 1995 Mar-Sep [RESTRICTED PHI POLICY]
18 39
BBC references, correspondence with Maimonides, 1995
18 40
Correspondence and photos of heart donor Kouch and recipient Louis Block, 1995-1996
R7 15
Correspondence, notes re: 1966 aborted transplant documentation, 1995-1997 [RESTRICTED PHI POLICY]
 
Michael Meyer Files, 1967-1986 [subseries]:
18 41
Human heart transplant F-1, 1967-1970
18 42
Kantrowitz first heart transplant - Meyer - Articles by Cabasson, Blanc, Joos [contains audiocassette], 1969
18 43
Heart Transplantation, Volume III Number 3, International Society for Heart Transplantation, [and correspondence], 1981-1984
18 44
Organ transplants and implants - Ethical issues articles [contains audiocassette], 1984-1986
18 45
A. Kantrowitz - First heart transplant, 1985 Aug
18 46
First American heart transplant [draft] [contains floppy disk], 1985