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Thomas C. Chalmers Papers 1927-1995
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Series 4: Publications, 1954-1995 [series]:

This series contains copies of Chalmers' published articles in such journals as the New England Journal of Medicine, The American Journal of Medicine, The Sciences, Controlled Clinical Trials, and The Mount Sinai Journal of Medicine. In addition, there are two bibliographies of Chalmers' publications. Among the many covered titles are clinical trials; meta-analysis; clinical gastroenterology and cardiology, and geriatrics.

The series is organized into 6 sub-series covering work he authored at the Mt. Sinai Clinical Trials Unit, the Technology Assessment Group, Harvard School of Public Health, and papers submitted for publication or in press. These sub-series follow Chalmers' original order and numbering system (which is roughly chronological) as found in folder 1 of Papers, Clinical Trials Unit, Mt. Sinai, 1965-1992.

 
Papers, Clinical Trials Unit, Mt. Sinai, 1965-1992 [subseries]:
47 1
Papers Published from Clinical Trials Unit, Mt. Sinai, 1992
47 2
1.1 "A Note on Fatality in Serum Hepatitis", 1965
47 3
1.2 "The Present Status of Shunts for Portal Hypertension in Cirrhosis", 1966
47 4
1.3 "The Transaminase Tests in Liver Disease", 1967
47 5
1.5 "Controlled Studies in Clinical Cancer Research", 1972
47 6
1.6 "Nonevaluable Patients in Clinical Cancer Research", 1975
47 7
1.7 "Effects of Ascorbic Acid on the Common Cold: An Evaluation of the Evidence", 1975
47 8
1.8 "Randomized Controlled Clinical Trials in Diseases of the Liver"
47 9
1.9 "Evidence Favoring the Use of Anticoagulants in the Hospital Phase of Acute Myocardial Infarction", 1977
47 10
1.10 "The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Control Trial", 1978
47 11
1.11 "In Defense of the VA Randomized Control Trial of Coronary Artery Surgery", 1978
47 12
1.12 "When and How to Stop a Clinical Trial: Invited Remarks", 1979
47 13
1.13 "Cost and Efficacy of the Substitution of Ambulatory for Inpatient Care", 1981
47 14
1.15 "The Clinical Trial", 1981
47 15
1.16 "A Survey of Clinical Trials of Antibiotic Prophylaxis in Colon Surgery: Evidence Against further Use of No-treatment Controls", 1981
47 16
1.17 "Randomized versus Historical Controls for Clinical Trials", 1982
47 17
1.18 "Who Will Fund Clinical Trials?", 1982
47 18
1.19 "Informed Consent, Clinical Research, and the Practice of Medicine", 1982
47 19
1.20 "The Inadequate Evidence for Short Hospital Stay after Hernia or Varicose Vein Stripping Surgery", 1982
47 20
1.21 "A Potpourri of RCT Topics", 1982
47 21
1.22 "Concluding Session: A General Discussion: Conference on Recent History of Randomized Clinical Trials", 1982
47 22
1.23 "Sensitivity and Specificity of Clinical Trials: Randomized vs. Historical Controls", 1983
47 23
1.24 "Physician Attitudes toward Applications of Computer Data Base Systems", 1983
47 24
1.25 "The Challenges of Clinical Measurement", 1983
47 25
1.26 "Impact of Randomized Control Trials on the Treatment of Alcohol Withdrawal", 1983
47 26
1.27 "Deficiencies of Clinical Trials of Alcohol Withdrawal", 1983
47 27
1.28 "Association of Adrenocorticosteroid Therapy and Peptic-ulcer Disease", 1983
47 28
1.29 "Bias in Treatment Assignment in Controlled Clinical Trials", 1983
47 29
1.30 "Peer Review Using a Paired-comparison Technique", 1984
47 30
1.31 "Should Mild Hypertension be Treated? An Attempted Meta-analysis of the Clinical Trials", 1985
47 31
1.32 "Should the Risk of AIDS Deter Hepatitis B Vaccination?", 1984
47 32
1.33 "Loss of Patients in Clinical Trials that Measure Long-term Survival following Myocardial Infarction", 1986
47 33
1.34 "An Analysis of the Costs of Ambulatory and Inpatient Care", 1986
47 34
1.35 "Meta-analyses of Randomized Controlled Trials", 1987
47 35
1.36 "Meta-analysis of Randomized Control Trials of Nicotine Chewing-gum", 1987
47 36
1.37 "The Lugano Statements on Controlled Clinical Trials", 1987
47 37
1.38 "Differing Attitudes of Industry and Academia towards Controlled Clinical Trials", 1986
47 38
1.41 "Publication Bias and Clinical Trials", 1987
47 39
1.42 "Antiplatelet Agents and Secondary Prevention of Stroke: A Meta-analysis of the Randomized Control Trials", 1988
47 40
1.43 "Dipyridamole in the Treatment of Agina Pectoris: A Meta-analysis", 1987
47 41
1.44 "Organization, Review, and Administration of Cooperative Studies (Greenberg Report): A Report from the Heart Special Project Committee to the National Advisory Heart Council, May 1967", 1988
47 42
1.45 "A Meta-analysis of Randomized Control Trials of Progestational Agents in Pregnancy", 1989
47 43
1.46 "Endoscopic Hemostasis: An Effective Therapy for Bleeding Peptic Ulcers", 1990
47
Abstracts, Clinical Trials Unit, Mt. Sinai, 1983-1987 [subseries]:
47 44
2.24 "Good Technology and Poor Clinical Science", 1983
47 45
2.41 "Technical Quality Assessment of Randomized Control Trials", 1987
47
Books and Chapters, Clinical Trials Unit, Mt. Sinai, 1981-1985 [subseries]:
47 46
3.1 "Emergency Diagnosis and Treatment of Gastrointestinal Hemorrhage", 1981
47 47
3.2 "Critique of Methods and Timing", 1981
47 48
3.3 "The Randomized Clinical Trial as a Basis for Therapeutic Decisions", 1982
47 49
3.4 "Early Termination of the Clinical Trial", 1982
47 50
3.5 "Randomized Clinical Trials and the Consumer", 1982
47 51
3.6 "The Control Bias in Clinical Trials", 1983
47 52
3.7 "Annotated Bibliography on the Impact of RCTs on Medical Practice", 1983
47 53
3.9 "Critical Decision making in Obtaining Laboratory Data", 1984
47 54
3.10 "Scientific Quality and the Journal of Holistic Medicine", 1985
47 55
3.11 "The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Controlled Trials: Survey of Two Sets of 'Negative' Trials"
47 56
3.12 "Meta-analysis of Randomized Control Trials: An Update of the Quality and Methodology"
47
Papers, Technology Assessment Group, Harvard School of Public Health, 1979-1992 [subseries]:
47 57
4.1 "Problems of Omissions in Communications on Clinical Trials", 1979
47 58
4.2 "Reporting Standards and Research Strategies for Controlled Trials: Agenda for the Editor", 1980
47 59
4.3 "Reporting on Methods in Clinical Trials"
47 60
4.4 "Combination of Results of Stated Precision: I. The Optimistic Case", 1982
47 61
4.5 "Reporting Clinical Trials in General Surgical Journals", 1984
47 62
4.6 "Perusing the Literature", 1984
47 63
4.7 "Using MEDLINE to Peruse the Literature", 1985
47 64
4.8 "Perusing the Literature: Methods of Accessing MEDLINE and Related Databases", 1985
47 65
4.9 "Using MEDLINE for Perusing the Literature: Software and Search Interface of Interest to the Medical Profession", 1985
47 66
4.10 "Perusing the Literature: Comparison of MEDLINE Searching with a Perinatal Clinical Trials Database", 1985
47 67
4.11 "Findings for Public Health from Meta-analysis", 1985
47 68
4.12 "Adjuvant Chemotherapy for Breast Cancer: A Pooled Estimate Based on Published Randomized Control Trials., 1987
47 69
4.13 "A Quality Assessment of Randomized Control Trials of Primary Treatment of Breast Cancer", 1986
47 70
4.14 "Quality Assessment of Randomized Control Trials in Dental Research: I Methods", 1986
47 71
4.15 "Quality Assessment of Randomized Control Trials in Dental Research: II Results: Periodontal Research", 1986
47 72
4.16 "Look before you Quote", 1986
47 73
4.17 "Meta-analysis in Clinical Medicine", 1987
47 74
4.18 "Cost-effectiveness Analysis of Periodontal Disease Control", 1987
47 75
4.19 "Adjuvant Therapy of Colorectal Cancer: Why We Still Don't Know", 1988
47 76
4.20 "The Poor Quality of Early Evaluations of Magnetic Resonance Imaging", 1988
47 77
4.21 "Commentary on Meta-analysis in Clinical Trials", 1988
47 78
4.22 "More on MEDLINE Searches", 1988
47 79
4.23 "Asbestos Exposure and Gastrointestinal Malignancy: Review and Meta-analysis", 1988
47 80
4.24 "An Assessment of Publication Bias Using a Sample of Published Clinical Trials", 1989
47 81
4.25 "A Meta-analysis of Alcohol Consumption in Relation to Risk of Breast Cancer", 1988
47 82
4.26 "Meta-analysis of Randomized Control Trials as a Method of Estimating Rare Complications of Non-steroidal Anti-inflammatory Drug Therapy", 1988
47 83
4.27 "Data Analysis in Gastroenterology: Vagotomy for Recurrent Duodenal Ulcer", 1988
47 84
4.28 "Methodological Considerations in the Analysis of Cost-effectiveness in Dentistry", 1989
47 85
4.29 "Chimiotherapie Adjuvante du Cancer Colorectal; qu' apprendre d'une Meta-analyse?"
47 86
4.32 "Publication Bias: A Problem in Interpreting Medical Data", 1988
47 87
4.33 "Publication Bias and Dissemination of Clinical Research", 1989
47 88
4.34 "A Comparison of Statistical Methods for Combining Event Rates from Clinical Trials", 1989
47 89
4.35 "The Effect of Study Design on Gain in Evaluations of New Treatments in Medicine and Surgery", 1988
47 90
4.36 "How Study Design Affects Outcomes in Comparisons of Therapy: I Medical", 1989
47 91
4.37 "How Study Design Affects Outcomes in Comparisons of Therapy: II Surgical", 1989
47 92
4.38 "Randomized Clinical Trials of Transdermal Nitroglycerin Systems for the Treatment of Angina: A Meta-analysis", 1988
47 93
4.39 "The Role of Clinical Trials in Healthcare: A Personal View", 1988
47 94
4.40 "Retrospective Analyses for Hypothesis Generation: A Commentary on the PACK Trial", 1989
47 95
4.42 "The Quality of Primary and Secondary Research and Meta-analysis", 1989
47 96
4.43 "Meta-analysis of Branched-chain Amino Acids in Hepatic Encephalopathy (Editorial)", 1989
47 97
4.44 "A Review of Clinical Research in Orthodontics", 1989
47 98
4.45 "Meta-analyses in Gastroenterology", 1989
47 99
4.46 "Symposium: Clinical Applications of Meta-analysis", 1989
47 100
4.47 "Meta-analytic Evidence Against Prophylactic Use of Lidocaine in Acute Myocardial Infarction", 1989
47 101
4.49 "A Cohort Study of Summary Reports of Controlled Trials", 1990
47 102
4.52 "Updated (Cumulative or Sequential) Meta-analyses of Histamine (H2) - Blockers in the Treatment of Bleeding Peptic Ulcers", 1990
47 103
4.54 "Some Statistical Methods for Combining Experimental Results", 1990
47 104
4.55 "The Need for Early Randomization in the Development of New Drugs for AIDS", 1990
47 105
4.57 "Split-mouth and Cross-over Designs in Dental Research", 1989
47 106
4.58 "Quality Assessment and Meta-analysis of Systemic Tetracycline Use in Chronic Adult Periodontitis", 1992
47 107
4.59 "Problems Induced by Meta-analysis", 1991
47 108
4.60 "A Meta-analysis of Physical Activity in the Prevention of Coronary Heart Disease", 1990
47 109
4.61 "An Empirical Study of the Possible Relation of Treatment Differences to Quality Scores in Controlled Randomized Clinical Trials", 1990
47 110
4.62 "Measuring Outcomes in Clinical Research", 1991
47 111
4.63 "Using Medical Registries and Data Sets for Technology Assessment", 1991
47 112
4.64 "Technology Assessment in the Connecticut Tumor Registry", 1991
47 113
4.65 "Use of the SEER Cancer Registry for Technology Assessment", 1991
47 114
4.66 "Technology Assessment in the Normative Aging Study", 1991
47 115
4.67 "Technology Assessment in the Veterans Administration Dental Longitudinal Study", 1991
47 116
4.68 "Technology Assessment in the Coronary Artery Surgery Study", 1991
47 117
4.69 "Using Medical Registries and Data Sets for Technology Assessment: An Overview of Seven Case Studies", 1991
47 118
4.71 "Meta119-analysis and Quality Assessment of Local Tetracycline use in Treatment of Chronic Adult Periodontitis", 1991
47 119
4.72 "Update on Technology Assessment in Dentistry", 1992
47 120
4.74 "Economic Analysis in Randomized Control Trials", 1992
47 121
4.75 "A Comparison of Results of Meta-analyses of Randomized Control Trials and Recommendations of Clinical Experts", 1992
47 122
4.76 "Cumulative Meta-analysis of Therapeutic Trials for Myocardial Infarction", 1992
47 123
4.79 "Assessment of the Efficacy and Safety of Antiarrhymic Therapy for Chronic Atrial Fibrillation: Observations on the Role of Trial Design and Implications of Drug-related Mortality", 1990
47 124
4.80 "Some Progress and Problems in Meta-analysis of Clinical Trials", 1992
47
Books and Chapters, Technology Assessment Group, Harvard School of Public Health, 1954-1991 [subseries]:
47 125
6.1 "Selected Quantitative Techniques", 1954
47 126
6.2 "Assessing Social Innovations: An Empirical Base for Policy", 1975
47 127
6.3 "How Well do Social Innovations Work?", 1975
47 128
6.4 "How Frequently Do Innovations Succeed in Surgery and Anesthesia?", 1977
47 129
6.5 "Progress in Surgery and Anesthesia: Benefits and Risks of Innovative Therapy"
47 130
6.6 "Combination of Results of Stated Precision: I. A More Realistic Case", 1984
47 131
6.7 Medical Uses of Statistics
47 132
6.8 "A Computer-driven Shift in the Practice of Medicine", n.d
47 133
6.9 "Clinical Trials of Treatment", 1986
47 134
6.10 "The Randomized Control Trials of Prevention of Myocardial Infarction", 1986
47 135
6.11 "Meta-analysis as Applied to Post-marketing Surveillance", 1987
47 136
6.12 "Randomized Control Trials and Meta-analysis of the Treatment of Cirrhosis of the Liver", 1987
47 137
6.13 "Hormone Therapy for the Maintenance of Pregnancy"
47 138
6.14 "Clinical Trials", 1988
47 139
6.18 "The Evaluations of Surgical Therapies", 1989
47 140
6.22 "Who is Interested in Clinical Trials? The Potential for and Methods of Minimizing Bias in Funded Research", 1991
47
Papers Submitted for Publication or in Press, 1990-1995 [subseries]:
47 141
7.1 "Declining Incidence of Ventricular Fibrillation", 1992
47 142
7.3 "Reporting the Results of Observational Studies: The Nutrition and Periodontal Disease Relationship"
47 143
7.6 "Patient Controlled Analgesia in the Postoperative Patient: Meta-analysis of Initial Randomized Control Trials", 1992
47 144
7.8 "Antipsychotic Drugs: Is More Worse? A Meta-analysis of the Published Randomized Control Trials", 1990
47 145
7.12 "The Design, Analysis, and Reporting of Research: Findings from Meta-analysis", 1990
47 146
Chalmers Bibliography, 1993
47 147
Reprints, 1992-1995