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W. French Anderson Papers 1977-1995
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Collection Scope and Content Note

Correspondence, laboratory and patient research data, clinical trial proposal development and IRB review records, meetings and conferences files, presentations, and videotapes document French Anderson's groundbreaking work to develop procedures for and to perform the first therapeutic introduction of gene therapy in humans. The collection concentrates almost exclusively on Anderson's tenure at the Molecular Hematology Branch of the National Heart, Lung and Blood Institute and in collaboration with the National Cancer Institute. It covers only the period of his career from 1977 to 1995. It does not include his post-NIH career at the University of Southern California.

Series 1, Biographical Information (1988-1992) is a small and disparate set of folders devoted to high school and college class reunions and some documentation of the terms of Anderson's move from NIH to the University of Southern California in 1992.

Series 2, Human Gene Therapy (1977-1992) contains fairly comprehensive documentation of Anderson's efforts to develop an effective gene therapy protocol, particularly between 1984 and 1990 when he concentrated on the method of introducing genes with a retrovirus. It is divided into two main sections comprising information about his two major breakthroughs: demonstration of the efficacy of gene therapy protocols (Tumor-Infiltrating Lymphocytes) and introduction of a healthy gene into a human being to correct a malfunctioning gene (Adenosine Deaminase). Each section contains subsets of correspondence, meeting agendas and reports relating to the lengthy process of developing protocols and receiving approval, applications and descriptions of experimental drugs, and data produced.

Series 3, Activities Outside NHLBI (1979-1992) is comprised of Anderson's collected materials relating to teaching engagements, lectures given, and meetings and conferences attended that were not directly involved with his lab work. They range from meetings at other NIH institutes to international conferences.

Series 4, Writings (1984-1990) is a small set of articles co-authored by Anderson, some written by others. All are devoted to gene therapy theory and practice as seen in the results of animal testing, mostly concerned with use of the ADA enzyme.

Series 5, Audiovisual Materials (1985-1995) are exclusively videocassettes and are organized into subseries developed by Anderson. Tapes in the Gene Therapy-related Subjects subseries (1986-1995) are mostly segments of commercial broadcast programs which address the concept of gene therapy. The Anderson Lectures subseries (1986-1994) present a series of speeches given by Anderson himself describing the potential of gene therapy. Clips from News Programs subseries (1989-1990) documents reporting done by various national television programs and networks about Anderson's gene therapy experiments.

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