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National Library of Medicine

Finding Aid to the Werner and Gertrude Henle Papers, 1955-1987

Archives and Modern Manuscripts Program, History of Medicine Division
Processed by Heather Lynn Willever
Processing Completed Nov. 4, 1993
Encoded by John P. Rees


Summary Information
Title: Werner and Gertrude Henle Papers
Creator: Henle, Werner, 1910-1987
Dates: 1955-1987
Extent: 12.1 linear feet (29 boxes)
Abstract:
Werner Henle, the son of a surgeon and grandson of anatomist-histologist Jacob Henle, was born in Dortmund, Germany. He attended the University of Munich from 1929-1930 and transferred to the University of Heidelberg in 1930 where he finished the course work needed for medical degree in 1934. Gertrude Szpingier was born in Mannheim, Germany and received her medical degree from the University of Heidelberg in 1936. The Henles are the most well known, however, for their research on Epstein-Barr virus. Their discovery of the relationship between Epstein-Barr virus and cancer demonstrated that the presence of certain viruses in the nucleus of a cell could transform a healthy cell into a malignant one.

Call number: MS C 491
Language: Collection materials primarily in English
Location: Materials stored onsite. History of Medicine Division. National Library of Medicine

Access Restrictions:

Collection is not restricted. Contact the Reference Staff for information regarding access.

Copyright and Re-use Information

Donor's copyrights were transferred to the public domain. Archival collections often contain mixed copyrights; while NLM is the owner of the physical items, permission to examine collection materials is not an authorization to publish. These materials are made available for use in research, teaching, and private study. It is the user's responsibility to research and understand any applicable copyright and re-publication rights not allowed by fair use. NLM does not grant permissions to publish.

Privacy Information

Archives and manuscript collections may contain materials with sensitive or confidential information that is protected under federal or state right to privacy laws and regulations. Researchers are advised that the disclosure of certain information pertaining to identifiable living individuals represented in any collection without the consent of those individuals may have legal ramifications for which the National Library of Medicine assumes no responsibility.

Preferred Citation:

Henle, Werner. Werner and Gertrude Henle Papers. 1955-1987. Located in: Modern Manuscripts Collection, History of Medicine Division, National Library of Medicine, Bethesda, MD; MS C 491.

Processing Information

The Henle's autobiography Growing up with virology : an annotated bibliography of Werner and Gertrude Henle : typescript, [1986?], was removed and separately cataloged as MS C 460.

Provenance:

Gift of Mrs. Gertrude Henle, 1987-1991. Acc. #476, 687, 712.

Related Materials/Collections

Growing Up with Virology, [1986?]; MS C 460

The Henles' autobiography appears to have been written by Werner Henle. Werner's narrative is insightful and full of personal vignettes that give a sense of the Henles' daily lives as scientists. The autobiography also provides an excellent chronology of their scientific research. Unfortunately, the autobiography is limited due to the absence of Gertrude's perspective. In his account of their professional lives, Werner did, however, address the issue of sexism and how it influenced his wife's career.


henleFinding Aid to the Werner and Gertrude Henle Papers, 1955-1987Archives and Modern Manuscripts Program, History of Medicine Division Version 1.0 History of Medicine Division, National Library of Medicine.
8600 Rockville Pike
Bethesda, Maryland, 20894
USA
Phone: (301) 402-8878 (Reference Desk)
Fax: (301) 402-0872
Email: hmdref@nlm.nih.gov
Machine-readable finding aid encoded by John P. ReesFinding aid is written in EnglishJuly 2004PUBLIC "-//National Library of Medicine::History of Medicine Division//TEXT (US::DNLM::MS C 491::Werner and Gertrude Henle Papers)//EN" "henle" converted from EAD 1.0 to 2002 by v1to02.xsl (sy2003-10-15).

National Library of Medicine

Finding Aid to the Werner and Gertrude Henle Papers, 1955-1987

Archives and Modern Manuscripts Program, History of Medicine Division
Processed by Heather Lynn Willever
Processing Completed Nov. 4, 1993
Encoded by John P. Rees

Descriptive Summary

Henle, Werner, 1910-1987Werner and Gertrude Henle Papers Dates: 1955-198712.1 linear feet (29 boxes)MS C 491 Materials stored onsite. History of Medicine Division. National Library of Medicine Abstract:Werner Henle, the son of a surgeon and grandson of anatomist-histologist Jacob Henle, was born in Dortmund, Germany. He attended the University of Munich from 1929-1930 and transferred to the University of Heidelberg in 1930 where he finished the course work needed for medical degree in 1934. Gertrude Szpingier was born in Mannheim, Germany and received her medical degree from the University of Heidelberg in 1936. The Henles are the most well known, however, for their research on Epstein-Barr virus. Their discovery of the relationship between Epstein-Barr virus and cancer demonstrated that the presence of certain viruses in the nucleus of a cell could transform a healthy cell into a malignant one.Collection materials primarily in EnglishProvenance:

Gift of Mrs. Gertrude Henle, 1987-1991. Acc. #476, 687, 712.

Access Restrictions:

Collection is not restricted. Contact the Reference Staff for information regarding access.

Copyright and Re-use Information

Donor's copyrights were transferred to the public domain. Archival collections often contain mixed copyrights; while NLM is the owner of the physical items, permission to examine collection materials is not an authorization to publish. These materials are made available for use in research, teaching, and private study. It is the user's responsibility to research and understand any applicable copyright and re-publication rights not allowed by fair use. NLM does not grant permissions to publish.

Privacy Information

Archives and manuscript collections may contain materials with sensitive or confidential information that is protected under federal or state right to privacy laws and regulations. Researchers are advised that the disclosure of certain information pertaining to identifiable living individuals represented in any collection without the consent of those individuals may have legal ramifications for which the National Library of Medicine assumes no responsibility.

Preferred Citation:

Henle, Werner. Werner and Gertrude Henle Papers. 1955-1987. Located in: Modern Manuscripts Collection, History of Medicine Division, National Library of Medicine, Bethesda, MD; MS C 491.

Processing Information

The Henle's autobiography Growing up with virology : an annotated bibliography of Werner and Gertrude Henle : typescript, [1986?], was removed and separately cataloged as MS C 460.

Related Materials/Collections

Growing Up with Virology, [1986?]; MS C 460

The Henles' autobiography appears to have been written by Werner Henle. Werner's narrative is insightful and full of personal vignettes that give a sense of the Henles' daily lives as scientists. The autobiography also provides an excellent chronology of their scientific research. Unfortunately, the autobiography is limited due to the absence of Gertrude's perspective. In his account of their professional lives, Werner did, however, address the issue of sexism and how it influenced his wife's career.

Biographical Note

Werner and Gertrude Szpingier Henle were a prodigious force in virology, immunology, and viral oncology during the second half the twentieth century. Researching together, they explored the various mechanisms involved in viral infection. A pragmatic research team, the Henles utilized their research to develop methods of diagnosis and immunization from infectious diseases.

The Henles first received acclaim for their work on infectious viruses. In 1943, they convincingly demonstrated the effectiveness of an influenza vaccine. The development of a rapid test for diagnosing mumps and an evaluation of a vaccine for mumps has also been credited to the Henles. In cooperation with Dr. Joseph Stokes, Jr., the Henles demonstrated how gamma globulin could be employed to hinder the development and proliferation of infectious hepatitis.

In addition to their contributions to disease prevention, the Henles' research on the mechanism of viral infections led to the discovery of three disease states: latency, persistency, and viral interference. Their research on viral interference laid the groundwork for the later discovery of interferon.

The Henles are the most well known, however, for their research on Epstein-Barr virus. They demonstrated the causal relationship between Epstein-Barr virus and infectious mononucleosis. Further research on Epstein-Barr led the Henles to conclude that EBV aided in the development of two human cancers, Burkitt's lymphoma and nasopharyngeal carcinoma. This significant relationship between Epstein-Barr virus and cancer demonstrated that the presence of certain viruses in the nucleus of a cell could transform a healthy cell into a malignant one. Applying this discovery to current cancer research, scientists are now studying how non-viral cancers are induced.

The Henles continued their research on Epstein-Barr virus and disease-induced immunodeficiencies such as acquired immunodeficiency syndrome, Hodgkins disease, ataxia-telangiectasia, Chediak-Higashi syndrome, and X-linked lymphoproliferative syndrome until Werner's death in 1987. After his death, Gertrude concluded their research.

Werner Henle, the son of a surgeon and grandson of anatomist-histologist Jacob Henle, was born in Dortmund, Germany on August 27, 1910. He attended the University of Munich from 1929-1930 and transferred to the University of Heidelberg in 1930 where he finished the course work needed for medical degree in 1934. The Nazi regime posed threats for Werner whose grandfather, Jacob Henle, was of Jewish descent (although baptized). Werner was classified as 25% non-Aryan and was not permitted to finish the internship required for the M.D. degree in any university, state or city hospital. Finding a hospital to finish the required internship was difficult. Fortunately, Werner was accepted at the Abteilung fur Pathologie of the Kaiser-Wilhelm-Institut fur Medizinische Forschung in Heidelberg. After being transferred to a low-profile department at this institute, Werner completed the needed internship for his medical degree. It became "increasingly clear" to Werner that he could "not stay in Germany and pursue a career to my liking." Thus, Werner came to Philadelphia, Pennsylvania in 1936 after being granted an instructorship at the University of Pennsylvania.

From 1936-1939, Werner served as an associate instructor in the microbiology department at the Medical School of the University of Pennsylvania. In 1937, Gertrude Szpingier, Werner's fiancee whom he had meet during his years at University of Heidelberg, emigrated to the United States. Gertrude was born in Mannheim, Germany on April 3, 1912. She received her medical degree from the University of Heidelberg in 1936. The day after Gertrude's arrival in America, she and Werner were married. Gertrude then joined Werner as a faculty member in the microbiology department at the University of Pennsylvania.

In 1939, Werner was promoted to associate professor in the virology department, University of Pennsylvania. In 1940, he became a member of the research team at the Children's Hospital of Philadelphia. One year later, Gertrude joined Werner as an associate professor of virology at the University of Pennsylvania and a member of the research staff at the Children's Hospital of Philadelphia. After more than 45 years service to the University of Pennsylvania, Werner and Gertrude retired from the University faculty in 1982. They continued their research at the Children's Hospital of Philadelphia until a few months prior to Werner's death in July 1987.

Werner and Gertrude were members of many health organizations and professional societies. They were active participants in the American Academia of Microbiology, the Tissue Culture Association, and the Society for American Microbiologists. Werner was also a member of the American Association of Immunologists, the Society for General Microbiology, the American Public Health Association, the New York Academia of Science, and the American Society for Cancer Research. Werner served as a consultant for the United States Surgeon General, the United States Army, and many different international health committees and hospital boards. Among their many awards and honors, the Henles received the Heart of Variety Show Bus Award in 1969; the Bristol-Meyers Award for Distinguished Achievement in Cancer Research in 1979; the Mead Johnson Award in 1950; the Billings Bronze Medal for Scientific Exhibit in 1953; the Smith, Kline, and French Award for Excellence in Research in 1971; the Robert-Koch-Medaille (one of West Germany's highest honors) in 1971; the Robert de Villeirs Award of the Leukemia Society of America in 1975; the Founders in Cancer Immunology Award from the Cancer Research Institute, Inc. in 1975; the Virus Cancer Program Award from the National Cancer Institute in 1975; the Scientific Award from the Philadelphia Chapter of the American Cancer Society in 1977; and the Children's Hospital's Gold Medal Award in 1983.

Werner Henle Chronology

1910Birth of Werner Henle in Dortmund, Germany on August 27
1936Emigrated to United States
1937Marriage to Gertrude Szpingier
1942Naturalized as an American Citizen
1987Death of Werner Henle on July 6
1929-30University of Munich
1930-34University of Heidelberg
1934M.D., University of Heidelberg
1935-36Internship, University of Heidelberg and Kaiser Wilhelm Institute
1971Honorary doctorate, University of Basel, Switzerland
1936-39Instructor, Department of Medical Microbiology, School of Medicine, University of Pennsylvania
1939Professor of Virology in Pediatrics, School of Medicine, University of Pennsylvania
1939Director, Division of Research Virology, Children's Hospital of Philadelphia
1947-63Director, Virus Diagnostic Laboratory, Reference Laboratory of the Department of Health, Commonwealth of Pennsylvania
1947-66Professor Virology, Department of Public Health and Preventive Medicine, School of Medicine, University of Pennsylvania
1982Professor Emeritus of Virology, School of Medicine, University of Pennsylvania
1951-87Member, World Health Organization Expert, Advisory Panel on Virus Diseases
1952-55Consultant to the Surgeon General, U.S. Public Health Service
1958-72Consultant to the Surgeon General, U.S. Armed Forces. Member, Commission on Viral Infections, U.S. Armed Forces
1962-70Chairman, Epidemiology, Hepatitis Subgroup, U.S. Armed Forces
1962-66Viral and Rickettsial Study Sections and Training Grant Committee
1962-67Consultant, Virus Cancer Program, National Cancer Institute
1968-73Scientific Advisory Board, Institute for Medical Research, Camden, New Jersey
1969-74Medical and Scientific Advisory Board, St. Jude Hospital, Memphis, Tennessee
1971-73Medical and Scientific Advisory Board, Leukemia Society of America
1974-76Member, National Cancer Advisory Board
1983Member, General Motors Awards Assembly

The collection contains correspondence, lab notebooks, and the Henles' unpublished autobiography (separately cataloged as MS C 460). The bulk of material is from the 1970's and 1980's. A smaller portion of the collection dates back to the 1950's and 1960's. The collection's prevalent emphasis is professional research work and correspondence. Little personal correspondence is included. The majority of materials are reflective of the research work Werner and Gertrude Henle conducted at the University of Pennsylvania and the Children's Hospital of Philadelphia. While Werner and his wife Gertrude conducted the majority of their research jointly, the correspondence is predominately Werner's. Gertrude's involvement, however, can be more clearly discerned in the lab notebooks in which she appeared to record lab results as frequently as Werner. The collection would be valuable to any scholar researching the history of virology and its practical application to disease prevention as well as such topics in scientific research as procuring funding for research, the necessity for collaboration in scientific studies and the issue of gender in scientific research.

Index Terms

These terms are indexed in the National Library of Medicine's online catalog LocatorPlus. Researchers wishing to find related materials should search the catalog using these terms.

    MeSH Subjects

    • Acquired Immunodeficiency Syndrome
    • Herpesvirus 4, Human
    • Epstein-Barr Virus Infections
    • Epstein-Barr Virus Nuclear Antigens
    • Allergy and Immunology
    • Leukocytes, Mononuclear
    • Burkitt Lymphoma
    • Nasopharyngeal Diseases
    • Virus Seriology
    • Virology
    Personal Names

    • Henle, Gertrude, 1912-
    • Alspaugh, Margaret
    • Biggar, Robert J.
    • Epstein, Alan
    • Friend, Charlotte, 1921-1987
    • Grose, Charles
    • Ho, John H. C.
    • Kaplan, Henry S., 1918-
    • Koldovsky, Paul Birnbaum
    • Levine, P. H. (Paul H.)
    • Magrath, Ian
    • Miller, George
    • Niederman, James C.
    • Pearson, Gary R.
    • Schooley, Robert T.
    Corporate Names

    • Children's Hospital of Philadelphia
    • University of Pennsylvania. School of Medicine
    Genre Terms

    • Laboratory Manuals

    Series Descriptions

    Correspondence, 1955-1987
    The Henles' correspondence dates from 1955 until Werner's death in 1987. The bulk of the correspondence was Werner's and is professional in nature. A small portion of the correspondence contains personal letters or greeting cards from family, friends, and colleagues. This series also contains research reports and conference presentations that were placed in the original correspondence boxes.

    General CorrespondenceBoxFolderContents11A, 1975-198712Ablashi, Dharam V., 1973-197713Ackerman, Rudolf, 1973-197714Albeck, Henrik, 1980-198615Alspaugh, Margaret A., 1977-198216American Cancer Society, 1978-198717American College of Physicians, Conference, March 17, 197218Andersson, Jan, 1982-198619Armstrong, Donald, 1978-1983110Ba - Be, 1973-1986111Be - Bo, 1974-1984112Br - By, 1975-198621Bar, Robert S., 1973-197422Bayer, Manfred E., 198023Berkel, A. Izzet, 1976-198724Berkow, Robert, 1975-198525Bethge, Heinz, 1980-198226Bieber, Charles P., 1981-198527Biggar, Robert J., 1975-1983Birnbaum, UrsulaAbstract: see Koldovsky, Paul and Ursula Birnbaum28Bjorkholm, Magnus, 1978-198429Blazar, Bruce, 1981-1983210Bocker, Jorg F., 1979-1980211Bornkamm, G. W., 1977-1986212Bruyn, Henry B., 1979-1981213Buckley, Johathan, 1983-1987214Ca - Ch, 1975-198631Cl - Co, 1975-198632Cr - Cu, 1975-198533Cancer Research Institute, Inc., 1975-197634Cantell, Kari, 1975-198635Casper, James, 1978-198636Cheeseman, Sarah H., 1978-197937Cheng, Y.C., 1978-198238Children's Cancer Research Center, Minutes of Executive Commitee, 1976-198039Cohen, Seymor S., 1979-1982310Cold Spring Harbor Laboratory, 1979-1983311Cornfeld, David, 1975-1978312Cortner, Jean A., 1975-1980313Da - Di, 1970-1987314 Do - Dw, 1975-1987315 Depue, Robert H., 1971-1976316 de Schryver, Andre, 1973317 de The, Guy Blaudin, 1968-197141 de The, Guy Blaudin, 1972-198342Diehl, Volker, 1975-198443Diwan, Arwin R., 1973-197744E, 1969-198545 Engelmann, Fritz K., 1978-198346Epstein, Alan, 1973-198247 Epstein, M. A. (Tony), 1970-198548Ernberg, Ingemar, 1976-198649Escobar, Mario R., 1974-1985410 Essex, Myron (Max), 1980-1986411Evans, Alfred S., 1970-1985412Evans, Joe Ann, 1976-1985413Fa - Fl, 1975-198651Fo - Fu, 1975-198752Falk, Lawrence, 1973-198553Faulkner, Ruth S., 1976-198454Federation of American Societies for Experimental Biology, Conference, Atlantic City, April 12, 197255Fiala, Milan, 1973-197756Finter, Norman, 1975-198657Friedman, Herman, 1980-198658Friend, Charlotte, 1973-197859 Fudenberg, Hugh H., 1979-1982510 Ga - Gl, 1971-1986511Go, 1975-1984512Gr - Gu, 1975-1987513Gallo, Robert C., 1976-1982514Gatti, Richard A., 1976-1978515 Geks, F.J., 1975-1985 516Ginsburg, Charles M., 1975-197761 Giraldo, G., 1975-1981 62Goetz, Otmar, 1975-198263Glaser, Ronald, 1973-198364Gotze, Heinz, 1975-198165Granoff, Allan, 1975-198366Greene, Mark H., 1976-198367Grose, Charles, 1973-198668Gross, Ludwick, 1975-198269Groupé, Vincent, 1975-1977610Gunvén, Peter, 1979-1982611 Guss, Maurice L., 1981-1983612Gutensohn, Nancy, 1975-1981 613Guvén, Peter, 1970-1977614Ha, 1973-1985615He, 1974-1986 616Hi - Hy, 1970-198771Halbert, Seymour P., 198172Hammond, Denman, 1975-197673Hampar, Berge, 1976-197974Henderson, Brian E., 1971-197775Hewetson, John F., 1968-197776Hinuma, Yorio, 1975-198177Hirsch, Martin S., 1977-198578Ho, John H.C., 1969-197479Ho, John H.C., 1975-1977710Ho, John H.C., 1978-1980711Hochberg, Fred H., 1974-1985 712Hollinshead, Ariel C., 1971-1974713Hong, Chang Lee, 1976-1977714Horwitz, Charles A., 1970-197581Horwitz, Charles A., 1976-197882Horwitz, Charles A., 1979-198183Horwitz, Charles A., 1982-198784Huang, Andrew T., 1975-198085Huang, Dolly P., 1975-197986Hummeler, Klaus, 1975-198787Humphreys, Robert E., 1979-198088I, 1976-198689Infectious Mononucleosis Symposium, New York, 1972810J, 1971-1987811Johansson, Bo, 1971-1977812Joncas, Jean H., 1975-1986813Judson, Susan, 1976-1983 91Ka - Ki, 1975-198692Kl - Ky, 1975-198593Kaplan, Henry S., 1969-197894Kaplan, Henry S., 1979-198495Kieff, Elliott, 1976-198596Killian, Cynthia, 1983-198497Klein, Gunnar O., 1981-198398Klemola, Erkki, 1969-197699Koldovsky, Paul and Ursula Birnbaum, 1966-1985101Kottaridis, S.D., 1979-1984102Kourilsky, Francois M., 1969-1976103Kwan, H.C., 1977-1982104La-Le, 1973-1987105Li-Lu, 1970-1986106Lanier, Anne P., 1976-1979107Lanier, Anne P., 1980-1987108Lennette, Edwin H., 1975-1986109Lenoir, Gilbert, 1978-19801010Levine, Alexandra M., 1983-1985111Levine, Paul H., 1971-1980112Levy, Jay, 1973-1986113Leyvraz, Serge, 1982-1986114Li, Frederick P., 1975-1983115Lindahl, Tomas, 1976-1980116Ma - Me, 1975-1986 117Mi - My, 1973-1985118Magrath, Ian, 1973-19879Mangold, Francoise, 1975-19821110 Maramorosh, Karl, 1975-19771111Marklund, Gunnar, 1985-19861112Mazaheri, Bahman, 1977-19821113 McAllister, Robert M., 1975-19781114McClain, Kenneth, 1982-19831115McKee, Kelly T., 1978-1981121Menezes, Jose, 1976-1985122Merino, Fernando, 1981-1987123Mietens, Carl, 1975-1986124 Milgram, Felix, 1975-1984125 Miller, George, 1973-1986 126Moloney, John B., 1976-1978127Morrow, Richard H., 1968-1976128Muller, Ferdinand, 1976-1983129Na - Ny, 1975-19871210Naegele, Robert F., 1978-19821211Nahmias, Andre J., 1976-19811212Nauts, Helen Coley, 1980-19861213Newcom, Samual, 1982-19831214Niederman, James C., 1970-19831215Nonoyama, Meihan, 1978-1986131O, 1975-1986132Oldstone, Michael B.A., 1976-1981133Olweny, Charles, 1974-1980134Osato, Toyoro, 1976-1979135Pa - Pu, 1975-1986136Pagano, Joseph S., 1978-1985137Pearson, Gary R., 1975-1980138Pearson, Gary R., 1981-1987139Pickering, Larry K., 1975-19791310Pike, Malcolm C., 1968-19711311Piver, M. Steven, 1983-19841312 Pollard, Morris, 1975-19811313 Pope, John H., 1979-19851314Potter, Howard Phelps, 1976-1979141Powell, Donald W., 1975-1980142Purtilo, David T., 1979-1985143Q, 1977-1981144Ra - Ri, 1975-1986145Ro - Ru, 1975-1986146Rabin, Harvey, 1979-1983147Rapp, Fred, 1975-1979148Rauscher, Frank J., 1969-1979149Rawls, William E., 1975-19761410Ray, Robert Gordon, 1971-19761411Reuman, Peter, 1976-19851412Rhoads, Jonathan E., 1975-19871413Ricken, Dieter, 1975-19831414Ringborg, Ulrik, 1978-19841415Rocchi, Giovanni, 1975-19811416Rodriguez, Jose E., 1975-19821417Roizman, Bernard, 1979-19861418Rubin, Robert H., 1977-19801419Sa - Se, 1975-1986151Sh - Sm, 1971-1986152Sn - Sw, 1975-1987153Salas, Rosalba, 1982-1986154Schooley, Robert T., 1981-1986155Sharon, Nehama, 1977-1979156Sheek, Martha R., 1978-1979157Smith, Stephen R., 1977-1984158Sohier, R., 1976-1979159Spiess, H., 1978-19831510Springer, Georg F., 1975-19771511Springer-Verlag, 19821512Steigman, Alex J., 1976-19781513Straus, Stephen E., 1983-1987161Strominger, Jack L., 1975-1984162Svedmyr, Erik, 1977-1981163Szigeti, Robert, 1981-1986164Ta - Tw, 1972-1987165ter Muelen, Volker, 1969-1979166Terasaki, Paul I., 1977-1978167Thorley-Lawson, David A., 1980-1985168Ug - Ut, 1975-1982169Va - Vo, 1969-19861610Van Zelst, Theodore W., 1984-19871611Vogt, Peter K., 1977-19801612Volsky, David J., 1982-19871613Wa - Wh, 1975-19871614Wi - Wu, 1969-19861615Warner, Helen B., 1979-19831616Weaver, Harry M., 1976-19771617Weller, Thomas H., 1972-19811618Wolf, Hans, 1975-19831619Ya - Yo, 1975-1985171Za - Zv, 1976-1987172Ziegler, John L., 1968-1979173zur Hausen, Harald, 1969-1977174zur Hausen, Harald, 1978-1986Research Subjects, 1955-1978BoxFolderContents181Acute respiratory illnesses of children: general information and protocol, 1959182Animal research, 1977-1978183Burkitts Lymphoma, 1968-1969184Burkitts Lymphoma, [1973]185Burkitts Lymphoma, patient cases, 1968-1974186Burkitts Lymphoma, prospective studies, 1968-1969187Established cell strains, 1955188Frederick Research Center conference, problems and prospects, Feburary 10 - 13, 1975189Frederick Research Center conference, R and D components of the early antigen complex, Feburary 10 -13, 19751810Frederick Research Center conference, viral capsid anitgen, Feburary 10 - 13, 19751811Human subjects/studies, 19751812Indirect immunofluorescence technique, n.d.1813Lab request forms, serology reports, 1968-19691814Patients included in Epstein Barr Virus research, 1968-19691815Report on stability of antibody levels to Epstein Barr Virus in the West Nile District, Uganda, 1969-19701816Third International Symposium on Oncogensis and Herpesviruses, 19771817Tumor collection proposal, 1959-1961Lab Notebooks, 1963-1987
    The Henles' lab notebooks span their research work from 1963 to 1987. In these lab notebooks, the Henles recorded the raw data from their experiments. The queries directing their research and an analysis of their findings are often included in the notebooks. The notebooks came to the library in binders with different headings. While the binders have been removed for preservation reasons, the integrity of the notebooks has been maintained. The headings that appeared on the binders were diverse - some listing researchers' names, others subject names, and still others geographical locations of the studies.

    To create organization in the collection, the notebooks were placed in boxes according to subject matter. Original binder headings have been preserved on the individual folders containing the notebooks. The box subject headings are as follows: Epstein-Barr Virus Associated Malignancies and Immunodeficiencies - General; Epstein-Barr Virus Associated Malignancies and Immunodeficiencies - Burkitts Lymphoma; Epstein-Barr Virus associated Malignancies and Immunodeficiencies -Nasopharyngeal Carcinoma; Epstein-Barr Virus Serology Studies; Herpes Studies; Infectious and Chronic Mononucleosis Studies; Miscellaneous Notebooks; Multiple Scoliosis Studies.

    Epstein-Barr Virus Associated Malignancies and ImmunodeficienciesBoxFolderContents191AIDS studies, 1985192American lymphocytic leukemia, 1972-1973193American lymphocytic leukemia, Children's Hospital of Philadelphia, 1981194B-cell lymphomas, 1979-1980195Clinical work, 1970-1975196Hamilton Fairley, G., Harlem Hospital, Steveson, Versuica (Hodgkins Disease and Lymphosarcoma), 1966-1970197Henderson, B.E., Newell (Hodgkin's Disease and Nasopharyngeal Cancer), 1971-1979198Immunodeficiencies: Conley, Merino, Osease, Roder, 1980-1985199Johansson, Bo #2 (Hodgkin's Diesease and Lymphoma), 1967-19781910Johansson, Bo #3 (Hodgkin's Disease and Lymphoma), 1978-1981201Johansson, Bo #4 (Hodgkin's Disease and Lymphoma), 1970-1985202Joyner, Claude R. (Iatrogenic Immunodeficiencies), 1968203Kourilsky, Francois M. (Leukemia, Hodgkin'S Disease and Lymphoproliferative Malignancies), 1966-1969204Kourilsky, Francois M., Paris (Acute Leukemia), 1967-1970205Leukemias, 1969-1971206Levine, Alexander U.S.C. (AIDS), 1983207St. Judes Hospital (Lymphoproliferative Malignancies), 1975208Stanford (hodgkin's Disease), 1969209Stanford (Hodgkin's Disease), 1970-19762010Tumors, 1969-1975Epstein-Barr Asssociated Malignancies and Immunodeficiencies: Burkitt's Lymphoma and CaPNSBoxFolderContents211Africa, 1968-1969212Africa, 1968-1978213American Burkitt's Lymphoma, 1980-1987214Early anitgen in Burkitt's Lymphoma, Kampala and Nairobi, 1970-1971215Experimental - Theresa (Burkitt's Lumphoma + CaPNS), 1969216Ghana: Depue, National Institutes of Health, 1971-1983217Ghana: Primary Infection in African Infants, 1977218Individual Cases: Burkitt's Lymphoma, 1963-1970219Magrath, National Institutes of Health, 1974-19792110Media/Inhibitors, 1965-19662111Stanford #2, 1975221Sweden #1: Klein and Old, 1965-1968222Sweden #2, 1969223Sweden #3, 1969224Sweden #4, 1970-1971225Sweden #5, 1971226Sweden #6, 1972-1974227Sweden #7, 1975-1978228Sweden #9, 1979-1981229West Nile, G.H., 1969-19742210West Nile and De The, 1969-1975Epstein-Barr Associated Malignancies and Immunodeficiences: Nasopharyngeal CarcinomaBoxFolderContents231Alaska #1, 1975-1981232Alaska #2, 1981-1984233Alaska #3, 1984-1985234Alaska #4, 1985-1987235De The and Ho, 1968-1972236"D" and "R" Antibody Studies, 1970-1971237EB2 (Studies of the damage drug concentrations have on EB2 in NPC and other cancers), 1970238Ho, Longitudinal Study, 1973-1976239Ho #2, 1976-19782310Mayo Clinic, 1981241Nasopharyngeal Carcinoma, [19--]242Strander Project, 1978-1980243Sweden #8, 1975-1976244Sweden #10 (Greenland Study), 1981-1985245Sweden #11, 1985-1986246U.S. NPC, St. Judes Children's Hospital, 1977-1980Epstein-Barr Virus Serology StudiesBoxFolderContents251Alspaugh, M.A. and Silverman, S. (immunoglobulin antibody studies), 1977-1981252Cleveland family study (seroepidemiology of EBV), 1967-1969253Cocultivations, infections, U-V experiments (transmission of EBV to various host systems), 1970-1971254EB immunoglobulin studies, 1965255EB2: immunoglobulin studies (primate/animal studies), 1966-1967256EB3 (primate studies), 1967257EB (early antigen studies), 1970-1971258EBNA: Lana et al, 1973-1974259EBV serology summaries, 19722510Electric-Nucleonics Labs, Inc. (IGg antibody studies on EBV), 19812511Experiments, 19692512IGA (immunoglobulin class of antibodies), 1974-19752513Massachusetts Institute of Technology: "CF with EB Cells", 1964-19682514Nadkarnis cell lines (arginine experiments), 1968-19692515Ponten cell lines, 1969-19702516Sumaya, C.V. (seroepidemiologic study of antibodies to EBV), 1972-19752517VCA Test and EBNA, 1972, 1977Herpes StudiesBoxFolderContents261Leinikki, Pauli, 1971-1972262Saimiri, H. (herpes studies on marmosets), 1972Infectious Mononucleosis And Chronic Mononucleosis VirusBoxFolderContents271Cherry; Mayo Clinic; George Klein (EBNA studies on chronic infectious mononucleosis), 1983-1986272Early antigen studies in infectious mononucleosis, Yale University, 1969-1971273Heterophil antibody response in infectious mononucleosis (Paul-Bunnell Anitgen), [19--]274Horwitz, Charles A. (IM), 1970-1973275Horwitz, Charles A. (IM), 1970-1975276Horwitz, Charles A. (CMV and IM), 1979-1980277Horwitz, Charles A. (CMV and IM Studies), 1980-1985278Horwitz, Charles A. (CMV), 1985-1987279New York Virus Watch, heterophile antibody tests, cytomegalovirus, spleen and acute IM, 1967-19682710Straus, Stephen E. and Cheney, Paul (Chronic IM), 1983-1986Miscellaneous NotebooksBoxFolderContents281Collaborative studies, Texas, 1981282Collaborative studies, 1976-1982283Collaborations #3; Virolab, psychiatry, Cordis, Israel, Pagano, Kazura, Levitt, Lennette, 1980-1986284Glaser, Judson, Miller, Shope, Springer, Ziegler, 1973-1985285Lennette, Evelyne T.: experimental, 1979-1980286Notes, abstracts, miscellaneous, 1969-1973287Unusual cases, 1974-1985Multiple SclerosisBoxFolderContents291Koln studies, 1975292Multiple sclerosis, 1969293Mice/Human Studies, 1974-1976294Polymorphonuclear leukocytes in mice sera, 1972-1973295Polymorphonuclear leukocytes in mice sera, 1973-1974

    Collection Scope and Content Note

    The collection contains correspondence, lab notebooks, and the Henles' unpublished autobiography (separately cataloged as MS C 460). The bulk of material is from the 1970's and 1980's. A smaller portion of the collection dates back to the 1950's and 1960's. The collection's prevalent emphasis is professional research work and correspondence. Little personal correspondence is included. The majority of materials are reflective of the research work Werner and Gertrude Henle conducted at the University of Pennsylvania and the Children's Hospital of Philadelphia. While Werner and his wife Gertrude conducted the majority of their research jointly, the correspondence is predominately Werner's. Gertrude's involvement, however, can be more clearly discerned in the lab notebooks in which she appeared to record lab results as frequently as Werner. The collection would be valuable to any scholar researching the history of virology and its practical application to disease prevention as well as such topics in scientific research as procuring funding for research, the necessity for collaboration in scientific studies and the issue of gender in scientific research.

    Contents List
    Box | Folder Title
     
    Correspondence, 1955-1987 [series]:

    The Henles' correspondence dates from 1955 until Werner's death in 1987. The bulk of the correspondence was Werner's and is professional in nature. A small portion of the correspondence contains personal letters or greeting cards from family, friends, and colleagues. This series also contains research reports and conference presentations that were placed in the original correspondence boxes.

     
    General Correspondence [subseries]:
    1 1
    A, 1975-1987
    1 2
    Ablashi, Dharam V., 1973-1977
    1 3
    Ackerman, Rudolf, 1973-1977
    1 4
    Albeck, Henrik, 1980-1986
    1 5
    Alspaugh, Margaret A., 1977-1982
    1 6
    American Cancer Society, 1978-1987
    1 7
    American College of Physicians, Conference, March 17, 1972
    1 8
    Andersson, Jan, 1982-1986
    1 9
    Armstrong, Donald, 1978-1983
    1 10
    Ba - Be, 1973-1986
    1 11
    Be - Bo, 1974-1984
    1 12
    Br - By, 1975-1986
    2 1
    Bar, Robert S., 1973-1974
    2 2
    Bayer, Manfred E., 1980
    2 3
    Berkel, A. Izzet, 1976-1987
    2 4
    Berkow, Robert, 1975-1985
    2 5
    Bethge, Heinz, 1980-1982
    2 6
    Bieber, Charles P., 1981-1985
    2 7
    Biggar, Robert J., 1975-1983
    Birnbaum, Ursula
    2 8
    Bjorkholm, Magnus, 1978-1984
    2 9
    Blazar, Bruce, 1981-1983
    2 10
    Bocker, Jorg F., 1979-1980
    2 11
     
    Bornkamm, G. W., 1977-1986
    2 12
    Bruyn, Henry B., 1979-1981
    2 13
    Buckley, Johathan, 1983-1987
    2 14
    Ca - Ch, 1975-1986
    3 1
    Cl - Co, 1975-1986
    3 2
    Cr - Cu, 1975-1985
    3 3
    Cancer Research Institute, Inc., 1975-1976
    3 4
    Cantell, Kari, 1975-1986
    3 5
    Casper, James, 1978-1986
    3 6
    Cheeseman, Sarah H., 1978-1979
    3 7
    Cheng, Y.C., 1978-1982
    3 8
    Children's Cancer Research Center, Minutes of Executive Commitee, 1976-1980
    3 9
    Cohen, Seymor S., 1979-1982
    3 10
    Cold Spring Harbor Laboratory, 1979-1983
    3 11
    Cornfeld, David, 1975-1978
    3 12
    Cortner, Jean A., 1975-1980
    3 13
    Da - Di, 1970-1987
    3 14
    Do - Dw, 1975-1987
    3 15
    Depue, Robert H., 1971-1976
    3 16
    de Schryver, Andre, 1973
    3 17
    de The, Guy Blaudin, 1968-1971
    4 1
    de The, Guy Blaudin, 1972-1983
    4 2
    Diehl, Volker, 1975-1984
    4 3
    Diwan, Arwin R., 1973-1977
    4 4
    E, 1969-1985
    4 5
    Engelmann, Fritz K., 1978-1983
    4 6
    Epstein, Alan, 1973-1982
    4 7
    Epstein, M. A. (Tony), 1970-1985
    4 8
    Ernberg, Ingemar, 1976-1986
    4 9
    Escobar, Mario R., 1974-1985
    4 10
    Essex, Myron (Max), 1980-1986
    4 11
    Evans, Alfred S., 1970-1985
    4 12
    Evans, Joe Ann, 1976-1985
    4 13
    Fa - Fl, 1975-1986
    5
    Fo - Fu, 1975-1987
    5 2
    Falk, Lawrence, 1973-1985
    5 3
    Faulkner, Ruth S., 1976-1984
    5 4
    Federation of American Societies for Experimental Biology, Conference, Atlantic City, April 12, 1972
    5
    Fiala, Milan, 1973-1977
    5 6
    Finter, Norman, 1975-1986
    5 7
    Friedman, Herman, 1980-1986
    5 8
    Friend, Charlotte, 1973-1978
    5 9
    Fudenberg, Hugh H., 1979-1982
    5 10
    Ga - Gl, 1971-1986
    5 11
    Go, 1975-1984
    5 12
    Gr - Gu, 1975-1987
    5 13
    Gallo, Robert C., 1976-1982
    5 14
    Gatti, Richard A., 1976-1978
    5 15
    Geks, F.J., 1975-1985
    5 16
    Ginsburg, Charles M., 1975-1977
    6 1
    Giraldo, G., 1975-1981
    6 2
    Goetz, Otmar, 1975-1982
    6 3
    Glaser, Ronald, 1973-1983
    6 4
    Gotze, Heinz, 1975-1981
    6 5
    Granoff, Allan, 1975-1983
    6 6
    Greene, Mark H., 1976-1983
    6 7
    Grose, Charles, 1973-1986
    6 8
    Gross, Ludwick, 1975-1982
    6 9
    Groupé, Vincent, 1975-1977
    6 10
    Gunvén, Peter, 1979-1982
    6 11
    Guss, Maurice L., 1981-1983
    6 12
    Gutensohn, Nancy, 1975-1981
    6 13
    Guvén, Peter, 1970-1977
    6 14
    Ha, 1973-1985
    6 15
    He, 1974-1986
    6 16
    Hi - Hy, 1970-1987
    7 1
    Halbert, Seymour P., 1981
    7 2
    Hammond, Denman, 1975-1976
    7 3
    Hampar, Berge, 1976-1979
    7 4
    Henderson, Brian E., 1971-1977
    7 5
    Hewetson, John F., 1968-1977
    7 6
    Hinuma, Yorio, 1975-1981
    7 7
    Hirsch, Martin S., 1977-1985
    7 8
    Ho, John H.C., 1969-1974
    7 9
    Ho, John H.C., 1975-1977
    7 10
    Ho, John H.C., 1978-1980
    7 11
    Hochberg, Fred H., 1974-1985
    7 12
    Hollinshead, Ariel C., 1971-1974
    7 13
    Hong, Chang Lee, 1976-1977
    7 14
    Horwitz, Charles A., 1970-1975
    8 1
    Horwitz, Charles A., 1976-1978
    8 2
    Horwitz, Charles A., 1979-1981
    8 3
    Horwitz, Charles A., 1982-1987
    8 4
    Huang, Andrew T., 1975-1980
    8 5
    Huang, Dolly P., 1975-1979
    8 6
    Hummeler, Klaus, 1975-1987
    8 7
    Humphreys, Robert E., 1979-1980
    8 8
    I, 1976-1986
    8 9
    Infectious Mononucleosis Symposium, New York, 1972
    8 10
    J, 1971-1987
    8 11
    Johansson, Bo, 1971-1977
    8 12
    Joncas, Jean H., 1975-1986
    8 13
    Judson, Susan, 1976-1983
    9 1
    Ka - Ki, 1975-1986
    9 2
    Kl - Ky, 1975-1985
    9 3
    Kaplan, Henry S., 1969-1978
    9 4
    Kaplan, Henry S., 1979-1984
    9 5
    Kieff, Elliott, 1976-1985
    9 6
    Killian, Cynthia, 1983-1984
    9 7
    Klein, Gunnar O., 1981-1983
    9 8
    Klemola, Erkki, 1969-1976
    9 9
    Koldovsky, Paul and Ursula Birnbaum, 1966-1985
    10 1
    Kottaridis, S.D., 1979-1984
    10 2
    Kourilsky, Francois M., 1969-1976
    10 3
    Kwan, H.C., 1977-1982
    10 4
    La-Le, 1973-1987
    10 5
    Li-Lu, 1970-1986
    10 6
    Lanier, Anne P., 1976-1979
    10 7
    Lanier, Anne P., 1980-1987
    10 8
    Lennette, Edwin H., 1975-1986
    10 9
    Lenoir, Gilbert, 1978-1980
    10 10
    Levine, Alexandra M., 1983-1985
    11 1
    Levine, Paul H., 1971-1980
    11 2
    Levy, Jay, 1973-1986
    11 3
    Leyvraz, Serge, 1982-1986
    11 4
    Li, Frederick P., 1975-1983
    11 5
    Lindahl, Tomas, 1976-1980
    11 6
    Ma - Me, 1975-1986
    11 7
    Mi - My, 1973-1985
    11 8
    Magrath, Ian, 1973-1987
    9
    Mangold, Francoise, 1975-1982
    11 10
    Maramorosh, Karl, 1975-1977
    11 11
    Marklund, Gunnar, 1985-1986
    11 12
    Mazaheri, Bahman, 1977-1982
    11 13
    McAllister, Robert M., 1975-1978
    11 14
    McClain, Kenneth, 1982-1983
    11 15
    McKee, Kelly T., 1978-1981
    12 1
    Menezes, Jose, 1976-1985
    12 2
    Merino, Fernando, 1981-1987
    12 3
    Mietens, Carl, 1975-1986
    12 4
    Milgram, Felix, 1975-1984
    12 5
    Miller, George, 1973-1986
    12 6
    Moloney, John B., 1976-1978
    12 7
    Morrow, Richard H., 1968-1976
    12 8
    Muller, Ferdinand, 1976-1983
    12 9
    Na - Ny, 1975-1987
    12 10
    Naegele, Robert F., 1978-1982
    12 11
    Nahmias, Andre J., 1976-1981
    12 12
    Nauts, Helen Coley, 1980-1986
    12 13
    Newcom, Samual, 1982-1983
    12 14
    Niederman, James C., 1970-1983
    12 15
    Nonoyama, Meihan, 1978-1986
    13 1
    O, 1975-1986
    13 2
    Oldstone, Michael B.A., 1976-1981
    13 3
    Olweny, Charles, 1974-1980
    13 4
    Osato, Toyoro, 1976-1979
    13 5
    Pa - Pu, 1975-1986
    13 6
    Pagano, Joseph S., 1978-1985
    13 7
    Pearson, Gary R., 1975-1980
    13 8
    Pearson, Gary R., 1981-1987
    13 9
    Pickering, Larry K., 1975-1979
    13 10
    Pike, Malcolm C., 1968-1971
    13 11
    Piver, M. Steven, 1983-1984
    13 12
    Pollard, Morris, 1975-1981
    13 13
    Pope, John H., 1979-1985
    13 14
    Potter, Howard Phelps, 1976-1979
    14 1
    Powell, Donald W., 1975-1980
    14 2
    Purtilo, David T., 1979-1985
    14 3
    Q, 1977-1981
    14 4
    Ra - Ri, 1975-1986
    14 5
    Ro - Ru, 1975-1986
    14 6
    Rabin, Harvey, 1979-1983
    14 7
    Rapp, Fred, 1975-1979
    14 8
    Rauscher, Frank J., 1969-1979
    14 9
    Rawls, William E., 1975-1976
    14 10
    Ray, Robert Gordon, 1971-1976
    14 11
    Reuman, Peter, 1976-1985
    14 12
    Rhoads, Jonathan E., 1975-1987
    14 13
    Ricken, Dieter, 1975-1983
    14 14
    Ringborg, Ulrik, 1978-1984
    14 15
    Rocchi, Giovanni, 1975-1981
    14 16
    Rodriguez, Jose E., 1975-1982
    14 17
    Roizman, Bernard, 1979-1986
    14 18
    Rubin, Robert H., 1977-1980
    14 19
    Sa - Se, 1975-1986
    15 1
    Sh - Sm, 1971-1986
    15 2
    Sn - Sw, 1975-1987
    15 3
    Salas, Rosalba, 1982-1986
    15 4
    Schooley, Robert T., 1981-1986
    15 5
    Sharon, Nehama, 1977-1979
    15 6
    Sheek, Martha R., 1978-1979
    15 7
    Smith, Stephen R., 1977-1984
    15 8
    Sohier, R., 1976-1979
    15 9
    Spiess, H., 1978-1983
    15 10
    Springer, Georg F., 1975-1977
    15 11
    Springer-Verlag, 1982
    15 12
    Steigman, Alex J., 1976-1978
    15 13
    Straus, Stephen E., 1983-1987
    16 1
    Strominger, Jack L., 1975-1984
    16 2
    Svedmyr, Erik, 1977-1981
    16 3
    Szigeti, Robert, 1981-1986
    16 4
    Ta - Tw, 1972-1987
    16 5
    ter Muelen, Volker, 1969-1979
    16 6
    Terasaki, Paul I., 1977-1978
    16 7
    Thorley-Lawson, David A., 1980-1985
    16 8
    Ug - Ut, 1975-1982
    16 9
    Va - Vo, 1969-1986
    16 10
    Van Zelst, Theodore W., 1984-1987
    16 11
    Vogt, Peter K., 1977-1980
    16 12
    Volsky, David J., 1982-1987
    16 13
    Wa - Wh, 1975-1987
    16 14
    Wi - Wu, 1969-1986
    16 15
    Warner, Helen B., 1979-1983
    16 16
    Weaver, Harry M., 1976-1977
    16 17
    Weller, Thomas H., 1972-1981
    16 18
    Wolf, Hans, 1975-1983
    16 19
    Ya - Yo, 1975-1985
    17 1
    Za - Zv, 1976-1987
    17 2
    Ziegler, John L., 1968-1979
    17 3
    zur Hausen, Harald, 1969-1977
    17 4
    zur Hausen, Harald, 1978-1986
     
    Research Subjects, 1955-1978 [subseries]:
    18 1
    Acute respiratory illnesses of children: general information and protocol, 1959
    18 2
    Animal research, 1977-1978
    18 3
    Burkitts Lymphoma, 1968-1969
    18 4
    Burkitts Lymphoma, [1973]
    18 5
    Burkitts Lymphoma, patient cases, 1968-1974
    18 6
    Burkitts Lymphoma, prospective studies, 1968-1969
    18 7
    Established cell strains, 1955
    18 8
    Frederick Research Center conference, problems and prospects, Feburary 10 - 13, 1975
    18 9
    Frederick Research Center conference, R and D components of the early antigen complex, Feburary 10 -13, 1975
    18 10
    Frederick Research Center conference, viral capsid anitgen, Feburary 10 - 13, 1975
    18 11
    Human subjects/studies, 1975
    18 12
    Indirect immunofluorescence technique, n.d.
    18 13
    Lab request forms, serology reports, 1968-1969
    18 14
    Patients included in Epstein Barr Virus research, 1968-1969
    18 15
    Report on stability of antibody levels to Epstein Barr Virus in the West Nile District, Uganda, 1969-1970
    18 16
    Third International Symposium on Oncogensis and Herpesviruses, 1977
    18 17
    Tumor collection proposal, 1959-1961
     
    Lab Notebooks, 1963-1987 [series]:

    The Henles' lab notebooks span their research work from 1963 to 1987. In these lab notebooks, the Henles recorded the raw data from their experiments. The queries directing their research and an analysis of their findings are often included in the notebooks. The notebooks came to the library in binders with different headings. While the binders have been removed for preservation reasons, the integrity of the notebooks has been maintained. The headings that appeared on the binders were diverse - some listing researchers' names, others subject names, and still others geographical locations of the studies.

    To create organization in the collection, the notebooks were placed in boxes according to subject matter. Original binder headings have been preserved on the individual folders containing the notebooks. The box subject headings are as follows: Epstein-Barr Virus Associated Malignancies and Immunodeficiencies - General; Epstein-Barr Virus Associated Malignancies and Immunodeficiencies - Burkitts Lymphoma; Epstein-Barr Virus associated Malignancies and Immunodeficiencies -Nasopharyngeal Carcinoma; Epstein-Barr Virus Serology Studies; Herpes Studies; Infectious and Chronic Mononucleosis Studies; Miscellaneous Notebooks; Multiple Scoliosis Studies.

     
    Epstein-Barr Virus Associated Malignancies and Immunodeficiencies [subseries]:
    19 1
    AIDS studies, 1985
    19 2
    American lymphocytic leukemia, 1972-1973
    19 3
    American lymphocytic leukemia, Children's Hospital of Philadelphia, 1981
    19 4
    B-cell lymphomas, 1979-1980
    19 5
    Clinical work, 1970-1975
    19 6
    Hamilton Fairley, G., Harlem Hospital, Steveson, Versuica (Hodgkins Disease and Lymphosarcoma), 1966-1970
    19 7
    Henderson, B.E., Newell (Hodgkin's Disease and Nasopharyngeal Cancer), 1971-1979
    19 8
    Immunodeficiencies: Conley, Merino, Osease, Roder, 1980-1985
    19 9
    Johansson, Bo #2 (Hodgkin's Diesease and Lymphoma), 1967-1978
    19 10
    Johansson, Bo #3 (Hodgkin's Disease and Lymphoma), 1978-1981
    20 1
    Johansson, Bo #4 (Hodgkin's Disease and Lymphoma), 1970-1985
    20 2
    Joyner, Claude R. (Iatrogenic Immunodeficiencies), 1968
    20 3
    Kourilsky, Francois M. (Leukemia, Hodgkin'S Disease and Lymphoproliferative Malignancies), 1966-1969
    20 4
    Kourilsky, Francois M., Paris (Acute Leukemia), 1967-1970
    20 5
    Leukemias, 1969-1971
    20 6
    Levine, Alexander U.S.C. (AIDS), 1983
    20 7
    St. Judes Hospital (Lymphoproliferative Malignancies), 1975
    20 8
    Stanford (hodgkin's Disease), 1969
    20 9
    Stanford (Hodgkin's Disease), 1970-1976
    20 10
    Tumors, 1969-1975
     
    Epstein-Barr Asssociated Malignancies and Immunodeficiencies: Burkitt's Lymphoma and CaPNS [subseries]:
    21 1
    Africa, 1968-1969
    21 2
    Africa, 1968-1978
    21 3
    American Burkitt's Lymphoma, 1980-1987
    21 4
    Early anitgen in Burkitt's Lymphoma, Kampala and Nairobi, 1970-1971
    21 5
    Experimental - Theresa (Burkitt's Lumphoma + CaPNS), 1969
    21 6
    Ghana: Depue, National Institutes of Health, 1971-1983
    21 7
    Ghana: Primary Infection in African Infants, 1977
    21 8
    Individual Cases: Burkitt's Lymphoma, 1963-1970
    21 9
    Magrath, National Institutes of Health, 1974-1979
    21 10
    Media/Inhibitors, 1965-1966
    21 11
    Stanford #2, 1975
    22 1
    Sweden #1: Klein and Old, 1965-1968
    22 2
    Sweden #2, 1969
    22 3
    Sweden #3, 1969
    22 4
    Sweden #4, 1970-1971
    22 5
    Sweden #5, 1971
    22 6
    Sweden #6, 1972-1974
    22 7
    Sweden #7, 1975-1978
    22 8
    Sweden #9, 1979-1981
    22 9
    West Nile, G.H., 1969-1974
    22 10
    West Nile and De The, 1969-1975
     
    Epstein-Barr Associated Malignancies and Immunodeficiences: Nasopharyngeal Carcinoma [subseries]:
    23 1
    Alaska #1, 1975-1981
    23 2
    Alaska #2, 1981-1984
    23 3
    Alaska #3, 1984-1985
    23 4
    Alaska #4, 1985-1987
    23 5
    De The and Ho, 1968-1972
    23 6
    "D" and "R" Antibody Studies, 1970-1971
    23 7
    EB2 (Studies of the damage drug concentrations have on EB2 in NPC and other cancers), 1970
    23 8
    Ho, Longitudinal Study, 1973-1976
    23 9
    Ho #2, 1976-1978
    23 10
    Mayo Clinic, 1981
    24 1
    Nasopharyngeal Carcinoma, [19--]
    24 2
    Strander Project, 1978-1980
    24 3
    Sweden #8, 1975-1976
    24 4
    Sweden #10 (Greenland Study), 1981-1985
    24 5
    Sweden #11, 1985-1986
    24 6
    U.S. NPC, St. Judes Children's Hospital, 1977-1980
     
    Epstein-Barr Virus Serology Studies [subseries]:
    25 1
    Alspaugh, M.A. and Silverman, S. (immunoglobulin antibody studies), 1977-1981
    25 2
    Cleveland family study (seroepidemiology of EBV), 1967-1969
    25 3
    Cocultivations, infections, U-V experiments (transmission of EBV to various host systems), 1970-1971
    25 4
    EB immunoglobulin studies, 1965
    25 5
    EB2: immunoglobulin studies (primate/animal studies), 1966-1967
    25 6
    EB3 (primate studies), 1967
    25 7
    EB (early antigen studies), 1970-1971
    25 8
    EBNA: Lana et al, 1973-1974
    25 9
    EBV serology summaries, 1972
    25 10
    Electric-Nucleonics Labs, Inc. (IGg antibody studies on EBV), 1981
    25 11
    Experiments, 1969
    25 12
    IGA (immunoglobulin class of antibodies), 1974-1975
    25 13
    Massachusetts Institute of Technology: "CF with EB Cells", 1964-1968
    25 14
    Nadkarnis cell lines (arginine experiments), 1968-1969
    25 15
    Ponten cell lines, 1969-1970
    25 16
    Sumaya, C.V. (seroepidemiologic study of antibodies to EBV), 1972-1975
    25 17
    VCA Test and EBNA, 1972, 1977
     
    Herpes Studies [subseries]:
    26 1
    Leinikki, Pauli, 1971-1972
    26 2
    Saimiri, H. (herpes studies on marmosets), 1972
     
    Infectious Mononucleosis And Chronic Mononucleosis Virus [subseries]:
    27 1
    Cherry; Mayo Clinic; George Klein (EBNA studies on chronic infectious mononucleosis), 1983-1986
    27 2
    Early antigen studies in infectious mononucleosis, Yale University, 1969-1971
    27 3
    Heterophil antibody response in infectious mononucleosis (Paul-Bunnell Anitgen), [19--]
    27 4
    Horwitz, Charles A. (IM), 1970-1973
    27 5
    Horwitz, Charles A. (IM), 1970-1975
    27 6
    Horwitz, Charles A. (CMV and IM), 1979-1980
    27 7
    Horwitz, Charles A. (CMV and IM Studies), 1980-1985
    27 8
    Horwitz, Charles A. (CMV), 1985-1987
    27 9
    New York Virus Watch, heterophile antibody tests, cytomegalovirus, spleen and acute IM, 1967-1968
    27 10
    Straus, Stephen E. and Cheney, Paul (Chronic IM), 1983-1986
     
    Miscellaneous Notebooks [subseries]:
    28 1
    Collaborative studies, Texas, 1981
    28 2
    Collaborative studies, 1976-1982
    28 3
    Collaborations #3; Virolab, psychiatry, Cordis, Israel, Pagano, Kazura, Levitt, Lennette, 1980-1986
    28 4
    Glaser, Judson, Miller, Shope, Springer, Ziegler, 1973-1985
    28 5
    Lennette, Evelyne T.: experimental, 1979-1980
    28 6
    Notes, abstracts, miscellaneous, 1969-1973
    28 7
    Unusual cases, 1974-1985
     
    Multiple Sclerosis [subseries]:
    29 1
    Koln studies, 1975
    29 2
    Multiple sclerosis, 1969
    29 3
    Mice/Human Studies, 1974-1976
    29 4
    Polymorphonuclear leukocytes in mice sera, 1972-1973
    29 5
    Polymorphonuclear leukocytes in mice sera, 1973-1974