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National Library of Medicine

Finding Aid to the Mason V. Hargett Papers, 1932-1986 (bulk 1938-1946)

History of Medicine Division
Processed by Willeke Sandler; Jim Labosier
Processing Completed May, 2003
Encoded by John P. Rees; Jim Labosier


Summary Information
Title: Mason V. Hargett Papers
Creator: Hargett, Mason V.
Dates: 1932-1986 (bulk 1938-1946)
Extent: 3.75 linear feet (4 boxes)
Abstract:
Mason V. Hargett contributed greatly to the field of tropical medicine with his work on the yellow fever vaccine, first with the Rockefeller Foundation in Brazil and then at the USPHS Rocky Mountain Laboratory in Montana. Hargett's research facilitated the introduction of a yellow fever vaccine produced without human serum.

Call number: MS C 533
Language: Collection materials primarily in English
Location: Materials stored onsite. History of Medicine Division. National Library of Medicine

Access Restrictions:

No restrictions on access.

Copyright and Re-use Information

Donor's copyrights were transferred to the public domain. Archival collections often contain mixed copyrights; while NLM is the owner of the physical items, permission to examine collection materials is not an authorization to publish. These materials are made available for use in research, teaching, and private study. It is the user's responsibility to research and understand any applicable copyright and re-publication rights not allowed by fair use. NLM does not grant permissions to publish.

Privacy Information

Archives and manuscript collections may contain materials with sensitive or confidential information that is protected under federal or state right to privacy laws and regulations. Researchers are advised that the disclosure of certain information pertaining to identifiable living individuals represented in any collection without the consent of those individuals may have legal ramifications for which the National Library of Medicine assumes no responsibility.

Preferred Citation:

Hargett, Mason V. Mason V. Hargett Papers. 1932-1986 (bulk 1938-1946). Located in: Archives and Modern Manuscripts Collection, History of Medicine Division, National Library of Medicine, Bethesda, MD; MS C 533.

Provenance:

Gift of Mason V. Hargett, 6/7/1988. Acession #518.


hargett533Finding Aid to the Mason V. Hargett Papers, 1932-1986 (bulk 1938-1946)History of Medicine Division. Archives and Modern Manuscripts Collection2.0History of Medicine Division, National Library of Medicine.
8600 Rockville Pike
Bethesda, Maryland, 20894
USA
Phone: (301) 402-8878 (Reference Desk)
Fax:(301) 402-0872
Email:hmdref@nlm.nih.gov
Machine-readable finding aid encoded by John P. Rees; Jim LabosierFinding aid is written in English

National Library of Medicine

Finding Aid to the Mason V. Hargett Papers, 1932-1986 (bulk 1938-1946)

History of Medicine Division
Processed by Willeke Sandler; Jim Labosier
Processing Completed May, 2003
Encoded by John P. Rees; Jim Labosier

Descriptive Summary

Hargett, Mason V.Mason V. Hargett Papers Dates: 1932-1986 (bulk 1938-1946)3.75 linear feet (4 boxes)MS C 533 Materials stored onsite. History of Medicine Division. National Library of Medicine Collection materials primarily in EnglishAbstract:Mason V. Hargett contributed greatly to the field of tropical medicine with his work on the yellow fever vaccine, first with the Rockefeller Foundation in Brazil and then at the USPHS Rocky Mountain Laboratory in Montana. Hargett's research facilitated the introduction of a yellow fever vaccine produced without human serum.Provenance:

Gift of Mason V. Hargett, 6/7/1988. Acession #518.

Access Restrictions:

No restrictions on access.

Copyright and Re-use Information

Donor's copyrights were transferred to the public domain. Archival collections often contain mixed copyrights; while NLM is the owner of the physical items, permission to examine collection materials is not an authorization to publish. These materials are made available for use in research, teaching, and private study. It is the user's responsibility to research and understand any applicable copyright and re-publication rights not allowed by fair use. NLM does not grant permissions to publish.

Privacy Information

Archives and manuscript collections may contain materials with sensitive or confidential information that is protected under federal or state right to privacy laws and regulations. Researchers are advised that the disclosure of certain information pertaining to identifiable living individuals represented in any collection without the consent of those individuals may have legal ramifications for which the National Library of Medicine assumes no responsibility.

Preferred Citation:

Hargett, Mason V. Mason V. Hargett Papers. 1932-1986 (bulk 1938-1946). Located in: Archives and Modern Manuscripts Collection, History of Medicine Division, National Library of Medicine, Bethesda, MD; MS C 533.

Biographical/Historical Note

Mason V. Hargett contributed greatly to the field of tropical medicine with his work on the yellow fever vaccine, first with the Rockefeller Foundation in Brazil and then at the USPHS Rocky Mountain Laboratory in Montana. Hargett's research facilitated the introduction of a yellow fever vaccine produced without human serum, thereby reducing the possibility of contamination that had existed before. Hargett designed, as well as headed, the Yellow Fever Unit at the Rocky Mountain Laboratory in the 1940s. He also worked with the US Public Health Service as a quarantine officer in Miami and Japan.

Mason V. Hargett was born in Farnhamville, Iowa, on April 24, 1904. He received his bachelor's degree from Asbury College in Kentucky in 1925, and his medical degree from Northwestern University in 1929. In 1929, Hargett opened his own practice in Yale, Oklahoma, but could not sustain his practice during the Depression. In 1931, Hargett joined the U.S. Public Health Service, and was stationed at the Coast Guard Academy in New London, Connecticut.

The U.S. Public Health Service was concerned about the possible spread of yellow fever to the United States from South America, and therefore, Hargett was sent to the London School of Tropical Medicine and Hygiene from January to June of 1937. He received his D.T.M. & H. from the Examining Board in England (Royal College of Physicians of London and the Royal College of Surgeons of England) in 1937.

Because of his training at the London School of Tropical Medicine and Hygiene, Hargett served as quarantine officer in Miami before he was sent to the International Health Division of the Rockefeller Foundation in Rio de Janeiro, Brazil. He was a guest student from October 1938 to November 1939, during which time he studied malaria, yellow fever and administration under Dr. Fred L. Soper, the director of the International Health Division in Brazil.

After returning to the United States, Hargett headed the unit established at the Rocky Mountain Laboratory in Hamilton, Montana to make yellow fever vaccine for U.S. Public Health Service. In 1942, the Yellow Fever Unit at the Rocky Mountain Laboratory took over production of the yellow fever vaccine for the U.S. military during World War II.

In 1946, Hargett was sent to Japan to serve at the quarantine officer for the U.S. Army, and to represent the military in the foreign quarantine operation. Due to the massive movement of people following the end of the war, the quarantine operation tried to prevent the introduction of diseases, particularly cholera and typhus, into Japan. Hargett returned to Hamilton, Montana in November 1946 after five months in Japan.

Hargett served at the Leprosarium in Louisiana for a short time before being transferred in 1947 to the Indian Medical Service in Billings, Montana, where he was Regional Medical Director for over two years.

When the Department of the Interior changed its policy concerning Regional Directors in 1950 (no longer privileging Commissioned Officers over Civil Service doctors), Hargett left the Indian Medical Service. He moved to Atlanta, where he worked with the hospital construction program. Hargett was in Atlanta from 1950 to 1952, then in San Francisco from 1952 until 1964, when he retired and moved back to Hamilton, Montana.


Photographs, diaries, research materials, slides and reports (1932-1986; 3.75 linear feet) document the official portion of Mason V. Hargett's career in tropical medicine. From 1938 to 1946, Hargett was instrumental in the research and production of yellow fever vaccine, including providing the vaccine for the U.S. military during World War II.

This collection consists primarily of records concerning Hargett's work with the International Health Division of the Rockefeller Foundation in Brazil (1938-1939) and with the Yellow Fever Unit at the Rocky Mountain Laboratory in Montana (1940-1946). The collection includes a significant number of photographs, chiefly from Hargett's time in Brazil, as well as materials relating to the procedure and production of yellow fever vaccine in the Rocky Mountain Laboratory.

Hargett was a guest student with the International Health Division of the Rockefeller Foundation in Rio de Janeiro, Brazil from October 1938 to November 1939. Series 2 contains documentary material from this period, including physician's manuals (in Portuguese), blank laboratory forms (the majority in Portuguese), a diary kept by Hargett, and photographs pertaining to malaria in Brazil and yellow fever control measures. The photographs document specific cases, prevention methods, facilities and equipment, and the Yellow Fever Service inspectors in Brazil. The Lantern Slides sub-series includes the lantern slides, some of which are negatives of many of the photographs included in this series.

From October 1940 to 1946, Hargett headed the Yellow Fever Unit at the Rocky Mountain Laboratory. The Rocky Mountain Laboratory was established in 1902 in response to the severe problem of Rocky Mountain spotted fever in the western half of the United States. The Laboratory became part of the Division of Infectious Diseases at the National Institute of Health in 1937. In 1948, the Rocky Mountain Laboratory and the Biologics Control Laboratory joined the Division of Infectious Diseases and the Division of Tropical Diseases of the National Institutes of Health to form the National Microbiological Institute. The Institute's name was changed in 1955 to the National Institute of Allergy and Infectious Diseases. In addition to the yellow fever vaccine unit, Rocky Mountain Laboratory also produced spotted fever vaccine. At the start of World War II, the Rockefeller Foundation in Brazil supplied the vaccine for U.S. military. In 1942, an outbreak in hepatitis B among U.S. troops was traced to infected human serum in the Rockefeller yellow fever vaccine. The Rocky Mountain Laboratory took over production of the vaccine for the military. By then Hargett's unit had developed a method of producing the vaccine without using human serum, which they called aqueous base vaccine. After the war, the demand for yellow fever vaccine dropped. Rocky Mountain Laboratory cut back on their operations, and undertook some research studies, including one study concerning the viability of the vaccine under various conditions. When Hargett was transferred to Japan, Harry W. Burruss (bacteriologist at the laboratory) took charge of operations. Production levels were low, and yellow fever vaccine production was closed down in 1957 and transferred to the National Drug Company's Biological Division in Swiftwater, Pennsylvania. Series 3 contains materials relating to Hargett's work at the Rocky Mountain Laboratory, including experiments reports, laboratory forms and unit orders, and technical reports, as well as a complete description of the method of production of yellow fever vaccine at Rocky Mountain Laboratory, including diagrams of equipment and photographs, compiled by H.W. Burruss. The series also includes tissue section slides of human cases of yellow fever and of diseases commonly confused with yellow fever.

Index Terms

These terms are indexed in the National Library of Medicine's online catalog LocatorPlus. Researchers wishing to find related materials should search the catalog using these terms.

    MESH Subjects

    • Malaria Vaccines
    • Yellow Fever Vaccine
    Personal Names

    • Burruss, Harry W.
    Corporate Names

    • Rockefeller Foundation. International Health Division
    • Rocky Mountain Laboratory
    • United States. Public Health Service
    Geographic Names

    • Brazil
    • Montana

    Series Descriptions

    Series 1: Personal and Biographical, 1985-198611 Resume, undated12 Interview transcript (Hargett, Mason V.), August 2, 198513 Interview transcript (Burruss, Harry W.), April 17, 1986 Series 2: Rockefeller Foundation, Brazil, 1930-194314 Diary, October, 1938 - November, 1939 Physicians' Manuals 15-6 Antilarvario I, II (2 vols), 1937-1938; 193717-8 Escriptorio I, II (2 vols), 1936-1937; 193719 Epidemiologia Entomologia Medico, 1935-1938110 Vacinacao, 1938111 Viscerotomia, 1932-1938112 Stegomyia Control Training Program - Bello Horizonte, 1939 Reports and Reprints 113 Aedes Aegypti mosquitoes - control, 1938-1943114 Aedes Aegypti - reprints, 1930-1932115 Malaria in northeastern Brazil - surveys, 1939116 Malaria in northeastern Brazil 1937-1939 - reprints, 1932-1939117-20 Laboratory forms, [1937; 1937-1939] Maps 21 Malaria, Brazil, 1938-193922-5 Yellow fever control measures, [1939-1940?] Series 3: Photographs, 1939 Malaria, Brazil 26 Doctor Castro examining for splenomegaly, May, 193926 Bar and sign halting motorists from the A. gambiae area, May, 193926 A few "Gambiae doctors" and friends, June, 193926 The Potengy river near Natal, R.G.N., June, 193926 The Pirangy river, June, 193926 Doctor M. A. Barber in Aracaty, Ceara, June, 193926 167 Anopheles gambiae and 21 culex recovered from mud house, July 5, 193926 Joao Gomes, aged 10 years, ill with malaria and kala azar, July 6, 193926 Joao Gomes, improving under treatment, [July 6, 1939]26 The home of Joao in the caranuba forest, [July 6, 1939]26 Typical A. gambiae infested village of the sertao, July, 193926 The Jagauribe river at Iguatu, Ceara, July, 193926 Pools in the bed of the Banabuihu river in Ceara, July, 193926 Measuring out paris green, July, 193926 A. gambiae breeding places, 193926 A puddle breeding A. gambiae, 193926 Pool in the bed of the Potengy river, 193926 A. gambiae love these open small pools, 193926 Additional stagnant pools in the bed of the Potengy river, 193926 The heat of the sun does not elevate the water temperature sufficiently. . ., 193926 Water will disappear later in the dry season, 193926 A muddy pool remaining in creek bottom near Russos, Ceara, 193926 Seepage water commonly creates ideal breeding places, 193926 Shaded pool in the caranuba forest near Russos, Ceara, which supported A. gambiae, 193926 Ferry landing at Aracaty, Ceara, showing the Jarauribe river, 193926 Dusting a pond with paris green to destroy possible breeding, 193926 A paris green duster with dermatitis caused by contact with chemical, [1939]26 The feet of the same man as above, [1939]26 Doctor Barber searching for larvae, [1939]26 Doctor Barber dusting water containing Anopheline larvae with paris green in a special demonstration, 193926 Doctor Barber drinking the water after dusting with paris green, [1939]26 Cars and trucks coming from A. gambiae area undergo disinfestations, [1939]26 Ready to commence spraying with pyrethrum-kerosene mixture, [1939]26 Doctors Wilson and Damasceno inspecting hut, [1939]26 Cars and trucks are thoroughly sprayed inside and out, [1939]26 Pump and sprayer are employed for boat and house work, [1939]26 An average six room adobe hut is sprayed for ten minutes, [1939]26 Two autos of the anti-gambiae service in Rio Grande de Norte, undated26 Home of the anti-gambiae laboratory in Aracaty, Ceara, undated26 Two typical boys of the gambiae country, undated26 Typical adobe hut of the gambaie country, undated26 Typical A. gambiae infested village in the caranuba section, undated26 A case of A. gambiae malaria, undated26 Taking a blood smear in Lagoa de Arroz, undated26 Men such as the one shown are emplyed to distribute atebrine and quinine to the sick, undated26 The principal means of transportataion in the dry sections of northeast Brazil, undated26 "Servicio de Malaria do Nordeste," directed by the Rockefeller Foundation, undated Yellow Fever Control Measures 27 Waterfall north of Carangola, February, 193927 Dr. Silveira and Dr. Hoering in conference, February, 193927 Typical mountain country near Carangola, February, 193927 Train awaiting a track at Porciuncula, February, 193927 A sprig of "fat grass", February, 193927 Milk being delivered at Manhaussu, February, 193927 Patent medicine poster, February, 193927 An everyday scene in Manhuassu, February, 193927 A poster on the door of a coffee mill, February, 193927 Oxen pulling a cart, February, 193927 Typical Laginha country, February, 193927 Preparing to ford the Jose Pedro river, February, 193927 Near Laghina, February, 193927 The leading hotel of Laginha, February, 193927 Kitchen staff of the Hotel Braga, February, 193927 Kitchen of the Hotel Braga, February, 193927 Delivering milk in Laginha, February, 193927 Doctors Silveira and Musa instructing pharmacist in use of viscerotome, February, 193927 A coffee-corn field near Laginha, February, 193927 Doctors with horses, ready to proceed to next case, February, 193927 Farming on mountainside, February, 193927 Examining patient in the fifth day of yellow fever, February, 193927 A typical view, February, 193927 Doctors Musa, Silveira and Hargett, February, 193927 Patient in the sixth day of yellow fever, February, 193927 Delivering wood for the cook-stove in Laginha, February, 193927 The Laginha road, February, 193928 A few physicians of the medical staff enjoy a game at the noon hour, undated28 Doctor Servulo-Lima, director, of the Brazilian Yellow Fever Service, undated28 The laboratory of the Brazilian Yellow Fever Service in Rio de Janeiro, undated28 Doctor Henrique A. Penna, in charge of vaccine preparation, and his staff, undated28 Doctor Joao Soares da Silveira, Director of the "Central Region", undated28 Doctors Milton Pessoa de Mello and Manoel Ferreira Neves, undated28 Doctor Carlos Mourao Ratton, undated28 The chief inspector of Bello Horizonte, undated28 Some of the 57 house-to-house inspectors, undated28 Part of the mosquito control force lined up for their monthly pay, undated28 Employees of the control service getting paid, undated28 Another view of the laboratory, undated28 Back porch of the Yellow Fever Service headquarters in Bello Horizonte, undated28 Entrance to the Yellow Fever Service headquarters in Bello Horizonte, undated28 A few of the cages harboring mice in the laboratory, undated28 Mouse cages are sterilized with cresol solution, undated28 Yellow fever vaccine is prepared in dust proof air-conditioned room, undated28 Sealing and labeling ampoules of vaccine, undated28 Eggshell cap cut loose by acetylene flame to remove embryo, undated28 Removing infective embryos for vaccine preparation, undated28 A sterile forcep for every embryo, undated28 Egg in position for cutting cap with flame, undated28 Filtration of vaccine is no longer practiced, undated28 Embryos are ground with glass balls and Alundun, undated28 Transferring embryo-serum mixture to centrifuge bottles, undated28 The finished vaccine, undated28 Filling ampoules with vaccine, undated29 Dragging rosewood logs out of the forest near Laginha, undated29 Friends and neighbors of Joao Carlos, undated29 Road repairs, undated29 The road from Laginha, undated29 A "Pau d'Arco" tree along the Jose Pedro river, undated29 Landemi Marmel in front of his home, undated29 Drawing blood from Landemi for virus isolation, undated29 The home of Landemi Marmel, undated29 A doorway in Landemi's home, undated29 Monkeys are common in forest near Landemi's home, undated29 Monkey jungle not far from where Landemi worked, undated29 Landemi holding his arm after blood was drawn, undated29 Near Landemi's home, undated29 Jungle near Landemi's home, undated29 Another view of Landemi's place, undated29 Another doorway of Landemi's home, undated29 Sebastiao Jose Sobeira ill in bed with yellow fever, undated29 Sebastiao's home, undated29 Jovelina Maria Ferreira, undated29 The home of Jovelina, undated29 Jungle near Jovelina's home, undated29 Forest cabin near Jovelina's home, undated29 Bringing Jovelina to the autopsy house, undated29 The autopsy house, undated29 Mosquito breeding near Jovelina's home, undated29 Capturing mosquitoes near Jovelina's place, undated29 Corn and coffee fields, undated29 Another view of Jovelina's home, undated29 A boy on trail near Jovelina's place, undated29 Jungle near Jovelina's home, undated29 Coffee mill serving as autopsy house, undated29 Bringing Ernesto to the coffee mill, undated29 Ernesto delivered to the coffee mill, undated29 A view near the coffee mill, undated29 Ernesto Cuiostomo Pampais, aged 13, undated29 Casket awaiting Ernesto, undated29 Bello Horizonte, undated29 Avenue in Bello Horizonte, undated29 Mailman in Bello Horizonte, undated29 Avenida Affonso Pena in Bello Horizonte, undated29 Delivering milk, undated29 One of many beautiful churches, undated29 Swimming pool, undated29 One of the many palms, undated29 A couple of boys at home, undated29 Birds in birdcages, undated29 Backyard of the Yellow Fever Service headquarters in Bello Horizonte, undated210 Aedes Aegypti search squad, undated210 Equipment carried by house-to-house inspectors, undated210 District map on the wall of a district headquarters, undated210 Flag of the district inspector at the gate, undated210 House with notices posted by inspector, undated210 Block numbers stenciled for service employees, undated210 Examining a grease trap, undated210 Culex breeding in a water trough, undated210 A special water container made of clay, undated210 Pile of scrap metal, undated210 Clay water jug typical in Brazil, undated210 Water containers often found in houses, undated210 Birdcages, undated210 Typical backyard scene in a better class home, undated210 Inspecting a hole in a papaya tree for breeding, undated210 Building under construction, undated210 Pool of water in the base of a tree, undated210 Concrete wash tub, undated210 Rubbers found in yard, undated210 Inspector breaking holes in a basin, undated210 Stone wall, a hideout for scorpions, undated210 Bamboo stumps are often breeding grounds, undated210 Inspector pouring oil in to a grease trap, undated210 Posting a notice on an uninhabited house, undated210 Sampling a stegomyia focus, undated210 A toilet flush box, undated210 Toilet sealed with old paper and oil, undated210 Sealed water tank, undated210 Oil used to end culex focus in bathtub, undated210 Two water tanks, undated210 A typical scene, undated210 Pool of water unsuitable for stegomyia but favorable for culex, undated210 Tank of anti-larvivirous minnows, undated210 Catch-basin sprayed to control stegomyia and culex breeding, undated210 Vases and urns filled with sand at cemetery, undated210 Moist sand supports flowers and plants, undated210 Standard method of carrying ship's water, undated210 Boat loaded with coconuts, undated210 Bucket dredge on ship not in use, undated210 Typical Brazilian coaster, undated210 Inspecting rainwater collections for breeding, undated210 Inspecting a barge just after a rain, undated210 Boats with produce coming to market, undated210 Inspector on horse, undated210 Farmhouse in Lagoa de Arroz, Ceara, undated210 Typical well in the country, undated210 Searching for country stegomyia, undated210 Standard means of water storage, undated210 Dry dung kept handy for anti-mosquito smudge making, undated210 [untitled], undated210 Special inspector and his helper, undated210 Draining the juice from a papaya tree, undated210 Trash found by inspectors hidden in lot, undated210 Sewer line man-hole, undated210 Typical vacant lot, undated210 Searching for hidden foci, undated210 Trash perforated and buried by hidden foci squad, undated210 Equipment carried by a capture inspector, undated210 Capture inspector at work, undated210 Zone Inspector Joaquim Janaurio de Souza, undated211-12 Lantern slides box indexes, undated3 Lantern slides (2 boxes), undated Series 4: Rocky Mountain Laboratory, Montana, 1940-1947213-15 Experiments, 1942-1946216 Yellow fever - clinical, 1943-1946217 Yellow fever - epidemiology, 1944218 Yellow fever - public relations, 1944219 Yellow fever vaccine - production, undated220 Yellow fever vaccine - reprints, 1942-1947221-22 Yellow fever unit orders, 1941-1945223 Laboratory forms, [1943-1946]224-28 Technical reports, 1940-19464 Tissue section slides (2 boxes), undated

    Collection Scope and Content Note

    Photographs, diaries, research materials, slides and reports (1932-1986; 3.75 linear feet) document the official portion of Mason V. Hargett's career in tropical medicine. From 1938 to 1946, Hargett was instrumental in the research and production of yellow fever vaccine, including providing the vaccine for the U.S. military during World War II.

    This collection consists primarily of records concerning Hargett's work with the International Health Division of the Rockefeller Foundation in Brazil (1938-1939) and with the Yellow Fever Unit at the Rocky Mountain Laboratory in Montana (1940-1946). The collection includes a significant number of photographs, chiefly from Hargett's time in Brazil, as well as materials relating to the procedure and production of yellow fever vaccine in the Rocky Mountain Laboratory.

    Hargett was a guest student with the International Health Division of the Rockefeller Foundation in Rio de Janeiro, Brazil from October 1938 to November 1939. Series 2 contains documentary material from this period, including physician's manuals (in Portuguese), blank laboratory forms (the majority in Portuguese), a diary kept by Hargett, and photographs pertaining to malaria in Brazil and yellow fever control measures. The photographs document specific cases, prevention methods, facilities and equipment, and the Yellow Fever Service inspectors in Brazil. The Lantern Slides sub-series includes the lantern slides, some of which are negatives of many of the photographs included in this series.

    From October 1940 to 1946, Hargett headed the Yellow Fever Unit at the Rocky Mountain Laboratory. The Rocky Mountain Laboratory was established in 1902 in response to the severe problem of Rocky Mountain spotted fever in the western half of the United States. The Laboratory became part of the Division of Infectious Diseases at the National Institute of Health in 1937. In 1948, the Rocky Mountain Laboratory and the Biologics Control Laboratory joined the Division of Infectious Diseases and the Division of Tropical Diseases of the National Institutes of Health to form the National Microbiological Institute. The Institute's name was changed in 1955 to the National Institute of Allergy and Infectious Diseases. In addition to the yellow fever vaccine unit, Rocky Mountain Laboratory also produced spotted fever vaccine. At the start of World War II, the Rockefeller Foundation in Brazil supplied the vaccine for U.S. military. In 1942, an outbreak in hepatitis B among U.S. troops was traced to infected human serum in the Rockefeller yellow fever vaccine. The Rocky Mountain Laboratory took over production of the vaccine for the military. By then Hargett's unit had developed a method of producing the vaccine without using human serum, which they called aqueous base vaccine. After the war, the demand for yellow fever vaccine dropped. Rocky Mountain Laboratory cut back on their operations, and undertook some research studies, including one study concerning the viability of the vaccine under various conditions. When Hargett was transferred to Japan, Harry W. Burruss (bacteriologist at the laboratory) took charge of operations. Production levels were low, and yellow fever vaccine production was closed down in 1957 and transferred to the National Drug Company's Biological Division in Swiftwater, Pennsylvania. Series 3 contains materials relating to Hargett's work at the Rocky Mountain Laboratory, including experiments reports, laboratory forms and unit orders, and technical reports, as well as a complete description of the method of production of yellow fever vaccine at Rocky Mountain Laboratory, including diagrams of equipment and photographs, compiled by H.W. Burruss. The series also includes tissue section slides of human cases of yellow fever and of diseases commonly confused with yellow fever.

    Contents List
    Box | Folder Title
     
    Series 1: Personal and Biographical, 1985-1986 [series]:
    1 1
    Resume, undated
    1 2
    Interview transcript (Hargett, Mason V.), August 2, 1985
    1 3
    Interview transcript (Burruss, Harry W.), April 17, 1986
     
    Series 2: Rockefeller Foundation, Brazil, 1930-1943 [series]:
    1 4
    Diary, October, 1938 - November, 1939
     
    Physicians' Manuals [subseries]:
    1 5-6
    Antilarvario I, II (2 vols), 1937-1938; 1937
    1 7-8
    Escriptorio I, II (2 vols), 1936-1937; 1937
    1 9
    Epidemiologia Entomologia Medico, 1935-1938
    1 10
    Vacinacao, 1938
    1 11
    Viscerotomia, 1932-1938
    1 12
    Stegomyia Control Training Program - Bello Horizonte, 1939
     
    Reports and Reprints [subseries]:
    1 13
    Aedes Aegypti mosquitoes - control, 1938-1943
    1 14
    Aedes Aegypti - reprints, 1930-1932
    1 15
    Malaria in northeastern Brazil - surveys, 1939
    1 16
    Malaria in northeastern Brazil 1937-1939 - reprints, 1932-1939
    1 17-20
    Laboratory forms, [1937; 1937-1939]
     
    Maps [subseries]:
    2 1
    Malaria, Brazil, 1938-1939
    2 2-5
    Yellow fever control measures, [1939-1940?]
     
    Series 3: Photographs, 1939 [series]:
     
    Malaria, Brazil [subseries]:
    2 6
    Doctor Castro examining for splenomegaly, May, 1939
    2 6
    Bar and sign halting motorists from the A. gambiae area, May, 1939
    2 6
    A few "Gambiae doctors" and friends, June, 1939
    2 6
    The Potengy river near Natal, R.G.N., June, 1939
    2 6
    The Pirangy river, June, 1939
    2 6
    Doctor M. A. Barber in Aracaty, Ceara, June, 1939
    2 6
    167 Anopheles gambiae and 21 culex recovered from mud house, July 5, 1939
    2 6
    Joao Gomes, aged 10 years, ill with malaria and kala azar, July 6, 1939
    2 6
    Joao Gomes, improving under treatment, [July 6, 1939]
    2 6
    The home of Joao in the caranuba forest, [July 6, 1939]
    2 6
    Typical A. gambiae infested village of the sertao, July, 1939
    2 6
    The Jagauribe river at Iguatu, Ceara, July, 1939
    2 6
    Pools in the bed of the Banabuihu river in Ceara, July, 1939
    2 6
    Measuring out paris green, July, 1939
    2 6
    A. gambiae breeding places, 1939
    2 6
    A puddle breeding A. gambiae, 1939
    2 6
    Pool in the bed of the Potengy river, 1939
    2 6
    A. gambiae love these open small pools, 1939
    2 6
    Additional stagnant pools in the bed of the Potengy river, 1939
    2 6
    The heat of the sun does not elevate the water temperature sufficiently. . ., 1939
    2 6
    Water will disappear later in the dry season, 1939
    2 6
    A muddy pool remaining in creek bottom near Russos, Ceara, 1939
    2 6
    Seepage water commonly creates ideal breeding places, 1939
    2 6
    Shaded pool in the caranuba forest near Russos, Ceara, which supported A. gambiae, 1939
    2 6
    Ferry landing at Aracaty, Ceara, showing the Jarauribe river, 1939
    2 6
    Dusting a pond with paris green to destroy possible breeding, 1939
    2 6
    A paris green duster with dermatitis caused by contact with chemical, [1939]
    2 6
    The feet of the same man as above, [1939]
    2 6
    Doctor Barber searching for larvae, [1939]
    2 6
    Doctor Barber dusting water containing Anopheline larvae with paris green in a special demonstration, 1939
    2 6
    Doctor Barber drinking the water after dusting with paris green, [1939]
    2 6
    Cars and trucks coming from A. gambiae area undergo disinfestations, [1939]
    2 6
    Ready to commence spraying with pyrethrum-kerosene mixture, [1939]
    2 6
    Doctors Wilson and Damasceno inspecting hut, [1939]
    2 6
    Cars and trucks are thoroughly sprayed inside and out, [1939]
    2 6
    Pump and sprayer are employed for boat and house work, [1939]
    2 6
    An average six room adobe hut is sprayed for ten minutes, [1939]
    2 6
    Two autos of the anti-gambiae service in Rio Grande de Norte, undated
    2 6
    Home of the anti-gambiae laboratory in Aracaty, Ceara, undated
    2 6
    Two typical boys of the gambiae country, undated
    2 6
    Typical adobe hut of the gambaie country, undated
    2 6
    Typical A. gambiae infested village in the caranuba section, undated
    2 6
    A case of A. gambiae malaria, undated
    2 6
    Taking a blood smear in Lagoa de Arroz, undated
    2 6
    Men such as the one shown are emplyed to distribute atebrine and quinine to the sick, undated
    2 6
    The principal means of transportataion in the dry sections of northeast Brazil, undated
    2 6
    "Servicio de Malaria do Nordeste," directed by the Rockefeller Foundation, undated
     
    Yellow Fever Control Measures [subseries]:
    2 7
    Waterfall north of Carangola, February, 1939
    2 7
    Dr. Silveira and Dr. Hoering in conference, February, 1939
    2 7
    Typical mountain country near Carangola, February, 1939
    2 7
    Train awaiting a track at Porciuncula, February, 1939
    2 7
    A sprig of "fat grass", February, 1939
    2 7
    Milk being delivered at Manhaussu, February, 1939
    2 7
    Patent medicine poster, February, 1939
    2 7
    An everyday scene in Manhuassu, February, 1939
    2 7
    A poster on the door of a coffee mill, February, 1939
    2 7
    Oxen pulling a cart, February, 1939
    2 7
    Typical Laginha country, February, 1939
    2 7
    Preparing to ford the Jose Pedro river, February, 1939
    2 7
    Near Laghina, February, 1939
    2 7
    The leading hotel of Laginha, February, 1939
    2 7
    Kitchen staff of the Hotel Braga, February, 1939
    2 7
    Kitchen of the Hotel Braga, February, 1939
    2 7
    Delivering milk in Laginha, February, 1939
    2 7
    Doctors Silveira and Musa instructing pharmacist in use of viscerotome, February, 1939
    2 7
    A coffee-corn field near Laginha, February, 1939
    2 7
    Doctors with horses, ready to proceed to next case, February, 1939
    2 7
    Farming on mountainside, February, 1939
    2 7
    Examining patient in the fifth day of yellow fever, February, 1939
    2 7
    A typical view, February, 1939
    2 7
    Doctors Musa, Silveira and Hargett, February, 1939
    2 7
    Patient in the sixth day of yellow fever, February, 1939
    2 7
    Delivering wood for the cook-stove in Laginha, February, 1939
    2 7
    The Laginha road, February, 1939
    2 8
    A few physicians of the medical staff enjoy a game at the noon hour, undated
    2 8
    Doctor Servulo-Lima, director, of the Brazilian Yellow Fever Service, undated
    2 8
    The laboratory of the Brazilian Yellow Fever Service in Rio de Janeiro, undated
    2 8
    Doctor Henrique A. Penna, in charge of vaccine preparation, and his staff, undated
    2 8
    Doctor Joao Soares da Silveira, Director of the "Central Region", undated
    2 8
    Doctors Milton Pessoa de Mello and Manoel Ferreira Neves, undated
    2 8
    Doctor Carlos Mourao Ratton, undated
    2 8
    The chief inspector of Bello Horizonte, undated
    2 8
    Some of the 57 house-to-house inspectors, undated
    2 8
    Part of the mosquito control force lined up for their monthly pay, undated
    2 8
    Employees of the control service getting paid, undated
    2 8
    Another view of the laboratory, undated
    2 8
    Back porch of the Yellow Fever Service headquarters in Bello Horizonte, undated
    2 8
    Entrance to the Yellow Fever Service headquarters in Bello Horizonte, undated
    2 8
    A few of the cages harboring mice in the laboratory, undated
    2 8
    Mouse cages are sterilized with cresol solution, undated
    2 8
    Yellow fever vaccine is prepared in dust proof air-conditioned room, undated
    2 8
    Sealing and labeling ampoules of vaccine, undated
    2 8
    Eggshell cap cut loose by acetylene flame to remove embryo, undated
    2 8
    Removing infective embryos for vaccine preparation, undated
    2 8
    A sterile forcep for every embryo, undated
    2 8
    Egg in position for cutting cap with flame, undated
    2 8
    Filtration of vaccine is no longer practiced, undated
    2 8
    Embryos are ground with glass balls and Alundun, undated
    2 8
    Transferring embryo-serum mixture to centrifuge bottles, undated
    2 8
    The finished vaccine, undated
    2 8
    Filling ampoules with vaccine, undated
    2 9
    Dragging rosewood logs out of the forest near Laginha, undated
    2 9
    Friends and neighbors of Joao Carlos, undated
    2 9
    Road repairs, undated
    2 9
    The road from Laginha, undated
    2 9
    A "Pau d'Arco" tree along the Jose Pedro river, undated
    2 9
    Landemi Marmel in front of his home, undated
    2 9
    Drawing blood from Landemi for virus isolation, undated
    2 9
    The home of Landemi Marmel, undated
    2 9
    A doorway in Landemi's home, undated
    2 9
    Monkeys are common in forest near Landemi's home, undated
    2 9
    Monkey jungle not far from where Landemi worked, undated
    2 9
    Landemi holding his arm after blood was drawn, undated
    2 9
    Near Landemi's home, undated
    2 9
    Jungle near Landemi's home, undated
    2 9
    Another view of Landemi's place, undated
    2 9
    Another doorway of Landemi's home, undated
    2 9
    Sebastiao Jose Sobeira ill in bed with yellow fever, undated
    2 9
    Sebastiao's home, undated
    2 9
    Jovelina Maria Ferreira, undated
    2 9
    The home of Jovelina, undated
    2 9
    Jungle near Jovelina's home, undated
    2 9
    Forest cabin near Jovelina's home, undated
    2 9
    Bringing Jovelina to the autopsy house, undated
    2 9
    The autopsy house, undated
    2 9
    Mosquito breeding near Jovelina's home, undated
    2 9
    Capturing mosquitoes near Jovelina's place, undated
    2 9
    Corn and coffee fields, undated
    2 9
    Another view of Jovelina's home, undated
    2 9
    A boy on trail near Jovelina's place, undated
    2 9
    Jungle near Jovelina's home, undated
    2 9
    Coffee mill serving as autopsy house, undated
    2 9
    Bringing Ernesto to the coffee mill, undated
    2 9
    Ernesto delivered to the coffee mill, undated
    2 9
    A view near the coffee mill, undated
    2 9
    Ernesto Cuiostomo Pampais, aged 13, undated
    2 9
    Casket awaiting Ernesto, undated
    2 9
    Bello Horizonte, undated
    2 9
    Avenue in Bello Horizonte, undated
    2 9
    Mailman in Bello Horizonte, undated
    2 9
    Avenida Affonso Pena in Bello Horizonte, undated
    2 9
    Delivering milk, undated
    2 9
    One of many beautiful churches, undated
    2 9
    Swimming pool, undated
    2 9
    One of the many palms, undated
    2 9
    A couple of boys at home, undated
    2 9
    Birds in birdcages, undated
    2 9
    Backyard of the Yellow Fever Service headquarters in Bello Horizonte, undated
    2 10
    Aedes Aegypti search squad, undated
    2 10
    Equipment carried by house-to-house inspectors, undated
    2 10
    District map on the wall of a district headquarters, undated
    2 10
    Flag of the district inspector at the gate, undated
    2 10
    House with notices posted by inspector, undated
    2 10
    Block numbers stenciled for service employees, undated
    2 10
    Examining a grease trap, undated
    2 10
    Culex breeding in a water trough, undated
    2 10
    A special water container made of clay, undated
    2 10
    Pile of scrap metal, undated
    2 10
    Clay water jug typical in Brazil, undated
    2 10
    Water containers often found in houses, undated
    2 10
    Birdcages, undated
    2 10
    Typical backyard scene in a better class home, undated
    2 10
    Inspecting a hole in a papaya tree for breeding, undated
    2 10
    Building under construction, undated
    2 10
    Pool of water in the base of a tree, undated
    2 10
    Concrete wash tub, undated
    2 10
    Rubbers found in yard, undated
    2 10
    Inspector breaking holes in a basin, undated
    2 10
    Stone wall, a hideout for scorpions, undated
    2 10
    Bamboo stumps are often breeding grounds, undated
    2 10
    Inspector pouring oil in to a grease trap, undated
    2 10
    Posting a notice on an uninhabited house, undated
    2 10
    Sampling a stegomyia focus, undated
    2 10
    A toilet flush box, undated
    2 10
    Toilet sealed with old paper and oil, undated
    2 10
    Sealed water tank, undated
    2 10
    Oil used to end culex focus in bathtub, undated
    2 10
    Two water tanks, undated
    2 10
    A typical scene, undated
    2 10
    Pool of water unsuitable for stegomyia but favorable for culex, undated
    2 10
    Tank of anti-larvivirous minnows, undated
    2 10
    Catch-basin sprayed to control stegomyia and culex breeding, undated
    2 10
    Vases and urns filled with sand at cemetery, undated
    2 10
    Moist sand supports flowers and plants, undated
    2 10
    Standard method of carrying ship's water, undated
    2 10
    Boat loaded with coconuts, undated
    2 10
    Bucket dredge on ship not in use, undated
    2 10
    Typical Brazilian coaster, undated
    2 10
    Inspecting rainwater collections for breeding, undated
    2 10
    Inspecting a barge just after a rain, undated
    2 10
    Boats with produce coming to market, undated
    2 10
    Inspector on horse, undated
    2 10
    Farmhouse in Lagoa de Arroz, Ceara, undated
    2 10
    Typical well in the country, undated
    2 10
    Searching for country stegomyia, undated
    2 10
    Standard means of water storage, undated
    2 10
    Dry dung kept handy for anti-mosquito smudge making, undated
    2 10
    [untitled], undated
    2 10
    Special inspector and his helper, undated
    2 10
    Draining the juice from a papaya tree, undated
    2 10
    Trash found by inspectors hidden in lot, undated
    2 10
    Sewer line man-hole, undated
    2 10
    Typical vacant lot, undated
    2 10
    Searching for hidden foci, undated
    2 10
    Trash perforated and buried by hidden foci squad, undated
    2 10
    Equipment carried by a capture inspector, undated
    2 10
    Capture inspector at work, undated
    2 10
    Zone Inspector Joaquim Janaurio de Souza, undated
    2 11-12
    Lantern slides box indexes, undated
    3
    Lantern slides (2 boxes), undated
     
    Series 4: Rocky Mountain Laboratory, Montana, 1940-1947 [series]:
    2 13-15
    Experiments, 1942-1946
    2 16
    Yellow fever - clinical, 1943-1946
    2 17
    Yellow fever - epidemiology, 1944
    2 18
    Yellow fever - public relations, 1944
    2 19
    Yellow fever vaccine - production, undated
    2 20
    Yellow fever vaccine - reprints, 1942-1947
    2 21-22
    Yellow fever unit orders, 1941-1945
    2 23
    Laboratory forms, [1943-1946]
    2 24-28
    Technical reports, 1940-1946
    4
    Tissue section slides (2 boxes), undated